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Seattle Seahawks vs Arizona Cardinals 11/21/21 NFL Picks, Odds, Predictions

Arizona Cardinals (8-2) vs. Seattle Seahawks (3-6)
November 21, 2021 4:25 pm EDT
The Line: Seattle Seahawks +2.5 / Arizona Cardinals -2.5; Over/Under: -50
(Get latest betting odds)

The Seattle Seahawks and Arizona Cardinals clash Sunday in a week 11 NFL action at Lumen Field in Seattle. The Arizona Cardinals look for a win after splitting their last four games. The Seattle Seahawks need a win after losing four of their last five games.

The Arizona Cardinals have won all five road games this season. Kyler Murray is completing 72.7 percent of his passes for 2,276 yards, 17 touchdowns and 7 interceptions. DeAndre Hopkins and Christian Kirk have combined for 1,089 receiving yards and 11 touchdowns, while AJ Green has 30 receptions. The Arizona Cardinals ground game is averaging 125.8 yards per contest, and James Conner leads the way with 493 yards and 11 touchdowns. Defensively, Arizona is allowing 18.9 points and 323 yards per game. Jordan Hicks leads the Arizona Cardinals with 74 tackles, Markus Golden has 9 sacks and Byron Murphy Jr. has 3 interceptions.

The Seattle Seahawks have lost three of their last four home games. Russell Wilson is completing 66.7 percent of his passes for 1,357 yards, 10 touchdowns and 3 interceptions. DK Metcalf and Tyler Lockett have combined for 1,208 receiving yards and 11 touchdowns, while Gerald Everett has 22 receptions. The Seattle Seahawks ground game is averaging 99.8 yards per contest, and Alex Collins leads the way with 345 yards and 2 touchdowns. Defensively, Seattle is allowing 20.7 points and 400.6 yards per game. Bobby Wagner leads the Seattle Seahawks with 101 tackles, Darrell Taylor has 4 sacks and Quandre Diggs has 3 interceptions.

The Cardinals are 18-7-3 ATS in their last 28 road games and 6-2 ATS in their last 8 games overall. The Seahawks are 1-4 ATS in their last 5 games in November and 3-1-1 ATS in their last 5 games in Week 11. The under is 10-3 in Cardinals last 13 road games. The under is 15-3 in Seahawks last 18 games overall. The Cardinals are 5-1 ATS in their last 6 meetings in Seattle and 6-2-1 ATS in their last 9 meetings.

It will obviously help to know if Murray and Hopkins are going to play for the Cardinals before locking in a bet. I’m assuming both will be cleared, given that the Cards are favored. The Seattle Seahawks are a complete mess right now, ranked 30th in total offense, 22nd in scoring offense and 31st in total defense. The Seahawks were just shutout last week. The Seahawks also aren’t having the same success at home that we’re used to seeing. Assuming the Cardinals have their stars back on offense, I’ll gladly lay the points here.

Randy Chambers's Free Pick: Arizona Cardinals -2.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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