Titans vs Rams Prediction 9/14/25 NFL Picks Today

The Los Angeles Rams and the Tennessee Titans meet in week 2 NFL action from Nissan Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Titans vs Rams Prediction.

Los Angeles Rams Recap

The Los Angeles Rams come into this game looking to add on to their season-opening 14-9 win over the Houston Texans to start the year 1-0. After this game, the Rams will head on the road for a game against the Philadelphia Eagles.

Rams Looking For Strong Start To Season

Matthew Stafford threw for 245 yards and a touchdown on 21 of 29 passing while Kyren Williams rushed for 66 yards and a touchdown. Puka Nacua led the Rams’ receiving group with 10 catches for 130 yards while Davante Adams had 4 catches for 51 yards and Davis Allen recorded the Rams’ lone receiving TD in the win. On defense, Kam Curl and Nate Landman each had a team-high 10 total tackles, while Byron Young, Tyler Davis and Jaylen McCollough each had a sack and Cobie Durant chipped in an interception for the Rams defensively in the win.

Why the Los Angeles Rams will win

• The Rams have won each of their last 11 Sunday games as favorites.
• The Titans have lost each of their last seven games.
• The Titans have failed to cover the spread in each of their last eight home games.
• The Rams have covered the spread in each of their last six road games.

Los Angeles Rams Player Prop Facts

• Davante Adams has scored two touchdowns in each of his last three road appearances against AFC South opponents.
• Kyren Williams has scored the first touchdown in four of his last five Sunday regular season appearances.
• Davante Adams has scored at least one touchdown in each of his last six road appearances against AFC South opponents.
• Matthew Stafford has recorded 240+ passing yards in each of his 15 previous September appearances against AFC opponents.
• Kyren Williams has recorded 69+ rushing yards in each of his last nine appearances following a home win.
• Puka Nacua has recorded 84+ receiving yards in eight of his last nine appearances against AFC opponents.
• Kyren Williams has recorded 95+ rushing and receiving yards in each of his last nine appearances following a home win.
• Matthew Stafford has recorded 22+ completions in each of his four previous appearances against the Titans.
• Heading into Week 2, Puka Nacua ranks T1st in the NFL in receptions (10) this season.

Tennessee Titans Recap

The Tennessee Titans come into this game looking to rebound from their 20-12 loss at the hands of the Denver Broncos last time out to start the year at 0-1. After this game, the Titans will head home for a game against the Indianapolis Colts.

Titans Looking To Shake Off Opening Loss

Cam Ward threw for 112 yards on 12 of 28 passing while Tony Pollard led the Titans on the ground with 60 rushing yards on 18 carries. Pollard led the Titans with 29 receiving yards while Calvin Ridley had a team-high 4 receptions for 27 yards and Chig Okonkwo added 3 receptions for 19 yards as well. On defense, Jarvis Brownlee Jr. and Cody Barton each had a team-high 9 total tackles with Brownlee Jr. adding 6 solo tackles while Jeffery Simmons had a sack. Xavier Woods and Roger McCreary each had an interception as well for Tennessee in the defeat. 

Why the Tennessee Titans will win

• The Titans have won four of their last five September games as home underdogs.
• The Rams have lost each of their last four road games in September.
• The Rams have failed to cover the spread in each of their last four road games in September.
• The Titans have covered the spread in five of their last six September games as underdogs against NFC opponents.

Tennessee Titans Player Prop Facts

• Calvin Ridley has scored at least one touchdown in five of his six previous Week 2 appearances.
• Tyler Lockett has recorded 59+ receiving yards in eight of his last nine Week 2 appearances.
• Tony Pollard has recorded 89+ rushing and receiving yards in each of his last six September appearances with his team as an underdog.
• Tony Pollard has recorded 70+ rushing yards in four of his last five September appearances against NFC opponents.
• Heading into Week 2, Joey Slye ranks T1st in the NFL in made field goals (4) this season.

Total Points Facts

• Seven of the Rams’ last eight games as favorites have gone UNDER the total points line.
• Eight of the Titans’ last 10 games as underdogs have gone OVER the total points line.

Titans vs Rams Prediction

I’m on the Rams here. It’s never easy to lay points on the road, and this early in the year, we’re still trying to figure out who some of these teams really are. However, the Rams looked solid defensively in week one, and Cam Ward still looks like he’s going to take time to adjust to things being played and the speed at which they’re played at the next level. The Rams are well-coached and this is still a solid spot for the Rams to start the year 2-0 in my eyes. Give me the Rams by a TD.