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Week 3: Minnesota Vikings vs Detroit Lions 9/25/22 NFL Picks, Predictions, Odds

Detroit Lions (1-1) vs. Minnesota Vikings (1-1)
September 25, 2022 1:00 pm EDT
The Line: Minnesota Vikings -8 / Detroit Lions +8; Over/Under: +50
(Get latest betting odds)

The Minnesota Vikings and Detroit Lions square off Sunday in a week 3 NFC North matchup in NFL action from U.S. Bank Stadium.

The Detroit Lions will be out to build on a 36-27 win over Washington in their last matchup. Jared Goff has thrown for 471 yards, 6 touchdowns and an interception on 57.7% passing while D’Andre Swift leads the Lions with 200 rushing yards and a touchdown. Amon-Ra St. Brown has a team-high 17 receptions for 180 receiving yards and 3 touchdowns to lead Detroit’s receiver group this season. On defense, Tracy Walker III leads the Lions with 18 total tackles while Jeff Okudah has a team-high 12 solo tackles. Aidan Hutchinson has a team-high 3 sacks as well this season for Detroit.


The Minnesota Vikings will try to rebound after a 24-7 loss to Philadelphia on Monday night football in week 2. Kirk Cousins has thrown for 498 yards, 3 touchdowns and 3 interceptions on 64.1% passing while Dalvin Cook leads the Vikings in rushing with 107 rushing yards this season. Justin Jefferson leads the Vikings’ receiving group with 15 grabs for 232 yards and a pair of touchdowns this season. On defense, Harrison Smith has a team-high 20 total tackles including 18 solo tackles while Danielle Hunter and D.J. Wonnum each have 2 sacks this season.

Detroit is 4-0 ATS in their last 4 division games and 5-1 ATS in their last 6 games overall while the over is 8-2 in their last 10 games in September. Minnesota is 4-1 ATS in their last 5 home games and 3-7 ATS in their last 10 games following a win while the over is 4-1 in their last 5 games following a loss.

I’ll give the Vikings some recognition, they’ve got some solid names on their roster. However, we saw a completely different Vikings team on Monday night than the one that whipped the Packers in the season opener. Now, the Vikings come in on a short week and take on a Lions team that’s hungry and is playing pretty well right now. The Lions are looking fantastic on offense and I think they can ride that offense to a cover at the very least here so give me Detroit plus the points.

Chris Ruffolo's Free Pick: Detroit +8

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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