College Football

Michigan State vs Ohio State Prediction 9-28-24 College Football Picks

Ohio State Buckeyes (3-0) vs. Michigan State Spartans (3-1)
September 28, 2024 7:30 pm EDT
The Line: Michigan State Spartans +23.5 / Ohio State Buckeyes -23.5; Over/Under: +48.5
(Get latest betting odds)

The Ohio State Buckeyes and Michigan State Spartans meet Saturday in week 5 college football action at Spartan Stadium. Here’s a Michigan State vs Ohio State Prediction. This article will include a Michigan State vs Ohio State Pick.

Ohio State Buckeyes Betting Preview

The Ohio State Buckeyes beat Akron, Western Michigan and Marshall, and they play Iowa next. The Ohio State Buckeyes look for a third straight 4-0 start to the season. Will Howard is completing 68.9 percent of his passes for 795 yards, 6 touchdowns, and 1 interception. Jeremiah Smith and Emeka Egbuka have combined for 547 receiving yards and 5 touchdowns, while Carnell Tate has 11 receptions.


The Ohio State Buckeyes ground game is averaging 241 yards per contest, and Quinshon Judkins leads the way with 336 yards and 5 touchdowns. Defensively, Ohio State is allowing 6.7 points and 180 yards per game. Lathan Ransom leads the Ohio State Buckeyes with 19 tackles, Tyleik Williams has 1.5 sacks and Gabe Powers has 1 interception.

Michigan State Spartans Betting Preview

The Michigan State Spartans beat Prairie View A&M, lost to Boston College and plays Oregon next. The Michigan State Spartans have won 3 of their last 4 home games. Aidan Chiles is completing 54.3 percent of his passes for 891 yards, 4 touchdowns and 7 interceptions. Nick Marsh and Montorie Foster Jr. have combined for 432 receiving yards and 2 touchdowns, while Jack Velling has 12 receptions.

The Michigan State Spartans ground game is averaging 153.8 yards per contest, and Kay’Ron Lynch-Adams leads the way with 271 yards and 1 touchdown. Defensively, Michigan State is allowing 14.3 points and 254.8 yards per game. Jordan Turner leads the Michigan State Spartans with 22 tackles, Khris Bogle has 3 sacks and Charles Brantley has 2 interceptions.

Why the Ohio State Buckeyes will win

  • Ohio State has won each of its last 42 games against non-AP-ranked teams.
  • Michigan State has lost each of its last 10 games against top-5 AP-ranked teams.
  • Michigan State has failed to cover the spread in each of its last seven games as an underdog against top-5 AP-ranked teams.
  • Ohio State has covered the spread in each of its last seven games against Michigan State.
  • Ohio State has won the first quarter in five of its last six road games against conference opponents.

Total Points Facts

  • Eight of Michigan State’s last nine home games in September have gone UNDER the total points line.
  • Four of Ohio State’s last five games as a road favorite have gone UNDER the total points line.

Matchup/League Facts

  • Michigan State ranks T128th among FBS teams for Q3 points per game this season (1.5).
  • Michigan State ranks 123rd among FBS teams for H2 points per game this season (7.3).
  • Ohio State ranks 1st among FBS teams for Q4 opponent points per game this season (0.0).
  • Ohio State ranks 1st among FBS teams for H2 opponent points per game this season (1.0).

Michigan State vs Ohio State Prediction

I considered the Michigan State Spartans and the points because this is a rivalry and while Sparty is awful offensively, this is still a physical and solid defensive team. The problem is, Ohio State is 8-0 SU and 7-1 ATS in the last 8 games against Michigan State, and Ohio State was 20 or more point favorites in 6 of those games. The Ohio State Buckeyes simply have more offensive horsepower and eventually things break loose. Ohio State has covered 4 of its last 6 games when favorites of 20 or more points. I’ll lay the chalk with the Buckeyes.

Randy Chambers's Free Pick: Michigan State Spartans +23.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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