Pirates vs Brewers Prediction 5/22/25 MLB Picks Today

The Milwaukee Brewers and Pittsburgh Pirates meet Thursday in MLB action at PNC Park. Here’s a Pirates vs Brewers Prediction. This article will include a Pirates vs Brewers Pick.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 24-26 on the year and play the Red Sox, Phillies, and Reds next. The Milwaukee Brewers are batting .229 on the season, have a .308 OBP, and a .349 slugging percentage. The Milwaukee Brewers’ pitching staff has a 4.11 ERA and a 1.32 WHIP. Brice Turang leads the Milwaukee Brewers with 51 hits and 20 RBI, while Jackson Chourio and Rhys Hoskins have combined for 96 hits and 53 RBI.

The Milwaukee Brewers didn’t announce a starting pitcher at the time this article was published.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 17-33 on the year and play the Diamondbacks, Padres, and Astros next. The Pittsburgh Pirates are batting .218 on the season, have a .298 OBP, and a .319 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 3.97 ERA and a 1.25 WHIP. Ke’Bryan Hayes leads the Pittsburgh Pirates with 43 hits and 15 RBI, while Bryan Reynolds and Isiah Kiner-Falefa have combined for 75 hits and 32 RBI.

Mike Burrows gets the ball for the Pittsburgh Pirates, and he is 1-0 with a 2.70 ERA and 2 strikeouts this season. This will be Burrows’ first career game against the Milwaukee Brewers.

Why the Pittsburgh Pirates will win

• The Brewers have lost each of their last six night games following a loss.
• The home team has won five of the Pirates’ last six games.
• The Brewers have failed to cover the run line in each of their last five night games following a loss.
• The Pirates have covered the run line in five of their last six games at PNC Park.
• The Brewers have lost the first inning in three of their last four night games against NL Central opponents.
• The Brewers have trailed after 5 innings in each of their last four night games against NL Central opponents.

Why the Milwaukee Brewers will win

• The Pirates have lost each of their last six night games against National League opponents following a win.
• The Brewers have won 10 of their last 12 night games against the Pirates following a home loss.
• The Pirates have failed to cover the run line each of their last six games against NL Central opponents that held a losing record.
• The Brewers have covered the run line in eight of their last nine road games against National League opponents following a loss.
• The Brewers have led after 5 innings in nine of their last 11 games at PNC Park against National League opponents that held a losing record.
• The Brewers have led after 3 innings in eight of their last nine games at PNC Park against NL Central opponents that held a losing record.

Pittsburgh Pirates Player Prop Facts

• Tommy Pham has recorded at least one hit in each of his last nine Thursday appearances against NL Central teams that held a losing record.
• Tommy Pham has recorded at least one Single in each of his last nine Thursday appearances against NL Central teams that held a losing record.
• Joey Bart has recorded at least one RBI in each of his last four home appearances against NL Central opponents that held a losing record.
• Bryan Reynolds has hit a home run in two of his last three home appearances against NL Central opponents that held a losing record.
• Oneil Cruz has scored a run in four of his last five appearances against NL Central opponents.

Milwaukee Brewers Player Prop Facts

• Jackson Chourio has recorded a Double in five of the Brewers’ last six games against NL opponents that held a losing record.
• William Contreras has recorded at least one hit in each of his last 12 road appearances against NL opponents.
• William Contreras has recorded a Single in each of his last nine road appearances against NL opponents.
• Christian Yelich has recorded at least one RBI in each of the Brewers’ last four night games against NL teams that held a losing record.
• Rhys Hoskins has hit a home run in each of the Brewers’ last two games against opponents that held a losing record.
• Jackson Chourio has scored at least one run in seven of the Brewers’ last eight games against NL opponents that held a losing record.

Pirates vs Brewers Prediction

The Brewers didn’t announce a starting pitcher at the time this article was published, but it doesn’t matter to me. The Pirates have been fade material all season, and a couple of wins don’t change much. The Pirates have won just six games since April 26 and have lost a $100 bettor more than $1,100 this season. Only the Orioles and Rockies have lost bettors more money this season than the Pirates. You should be blindly fading the Pirates. I don’t care who takes the mound for the Brewers. Give me the road team.