
Athletics vs Angels Prediction 9/5/25 MLB Picks Today
Athletics vs Angels
September 5, 2025 9:38 pm EDT
The Line: Angels -150 / Over/Under: 9
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In this article, we will formulate an Athletics vs Angels Prediction for this MLB game on Friday, September 5th at the Angel Stadium in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.
Los Angeles Angels Preview
The Los Angeles Angels have a 66-74 record this season and are sitting on the 4th place of the AL West. The Angels have a 34-35 home record and 75-62 in over/under They are coming off a 3-4 road defeat by the Royals, that ended their two-game winning streak. Under is 6-1 in their last 7 games and are playing the Mariners and the Twins next.
The Angels have a .228 batting average this season, .302 OBP and .401 Slugging percentage. LA’s pitching staff has a 4.70 ERA and 1.42 WHIP. Zach Neto leads the Angels with 125 hits, while Nolan Schanuel is the team’s best hitter with a .266 batting average. Taylor Ward leads the team with 94 RBI, while Jo Adell adds a team-high 33 home runs.
Jose Soriano (R) is the projected starting pitcher for the Angels, and he has a 10-9 record, 3.68 ERA and 1.33 WHIP.
Athletics Preview
The Athletics have a 64-77 record this season and are sitting on the last place of the AL West. The Athletics have a 35-37 road record and are 71-64 in over/under. They are coming off a 1-5 road defeat by the Cardinals, and are 1-5 in their last 6 games. They are playing the Red Sox and the Reds next.
The Athletics have a .253 batting average this season, .318 OBP and .432 Slugging percentage. Athletics’ pitching staff has a 4.81 ERA and 1.37 WHIP. Brent Rooker leads the Athletics with 149 hits, while Jacob Wilson is the team’s best hitter with a .315 batting average. Tyler Soderstrom adds a team-high 81 RBI, while Shea Langeliers adds a team-high 29 home runs.
Mason Barnett (R) is the projected starter for the Athletics, and he has a 0-1 record, 11.25 ERA, and 2.00 WHIP.
Why the Los Angeles Angels will win
- The Athletics have lost each of their last six road games against AL West opponents that held a losing record.
- The Angels have won each of their last four home games against the Athletics.
- The Angels have covered the run line in eight of their last nine home games against AL West opponents following a loss.
- The Athletics have failed to cover the run line in each of their last four games against AL West opponents.
- The Angels have led after 3 innings in four of their last five games as home favorites against AL West opponents.
- The Athletics have trailed after 5 innings in each of their last four games against AL West opponents.
- The Angels have won the first inning in three of their last four games as home favorites against AL West opponents.
Why the Athletics will win
- The Athletics have won each of their last six games as road underdogs following a loss.
- The Angels have lost seven of their last eight games as favorites against AL West opponents following a road loss.
- The Athletics have covered the run line in 14 of their last 15 games as road underdogs.
- The Angels have failed to cover the run line in each of their last seven games as favorites following a road loss.
- The Angels have trailed after 5 innings in seven of their last eight night games against American League opponents that held a losing record.
- The Angels have lost the first inning in each of their last five night games against AL West opponents that held a losing record.
- The Angels have trailed after 3 innings in each of their last four night games against AL West opponents that held a losing record.
Total Runs Facts
- Each of the Angels’ last five night games against American League opponents have gone UNDER the total runs line.
- Six of the Athletics’ last seven games as underdogs have gone OVER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Angels’ last five games as favorites against AL West opponents.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Athletics’ last four night games.
Matchup/League Facts
- The Angels rank 30th in the league for strikeouts against this season (1376).
- The Angels rank 30th in the league for walks allowed this season (531).
- The Athletics rank 2nd in the league for doubles this season (261).
- The Athletics rank 29th in the league for home runs allowed this season (198).
Athletics vs Angels Prediction
The Angels are 8-2 in their last 10 head-to-head meetings against the Athletics, having won their last three meetings in Los Angeles. Over is 7-2 in their last 9 meetings.
In this Athletics vs Angels Prediction, the Angels are coming as -150 home favorites. Barnett was torched in his only start for the Athletics, while Soriano has been lights out lately, with back-to-back shutout starts against the Astros and the Rangers, and three shutouts in his last four starts. In his previous home start against the A’s this season, he gave up only one run, and he now faces a struggling Athletics squad. Take the Angels to get the job done at home in this one.