Pistons vs Trail Blazers Prediction 12/5/25 NBA Picks Today
Portland Trailblazers (9-13) vs. Detroit Pistons (17-5)
December 5, 2025 7:30 pm EDT
The Line: Detroit Pistons -7.5; Over/Under: 234.5
(Get latest betting odds)
The Portland Trail Blazers and Detroit Pistons meet Friday in NBA action at the Little Caesars Arena. Here’s a Pistons vs Trail Blazers Prediction. This article will include a Pistons vs Trail Blazers Pick.
Portland Trail Blazers Betting Preview
The Portland Trail Blazers lost to the Raptors, beat the Cavs, and they play the Grizzlies next. The Trail Blazers have lost 11 of their last 16 games.
The Portland Trail Blazers are averaging 118.3 points on 44.3 percent shooting and allowing 121.2 points on 48.2 percent shooting. Deni Avdija is averaging 25.8 points and 7.1 rebounds, while Shaedon Sharpe is averaging 20.9 points and 4.8 rebounds. Jerami Grant is the third double-digit scorer and Jrue Holiday is grabbing 5.3 rebounds. The Portland Trail Blazers are shooting 32.9 percent from beyond the arc and 79.2 percent from the free-throw line. The Portland Trail Blazers are allowing 36.6 percent shooting from deep and are grabbing 45.9 rebounds per game.
Detroit Pistons Betting Preview
The Detroit Pistons beat the Hawks, lost to the Bucks, and they play the Bucks next. The Pistons have won 15 of their last 18 games.
The Detroit Pistons are averaging 119.8 points on 48.8 percent shooting and allowing 114 points on 44.6 percent shooting. Cade Cunningham is averaging 28.8 points and 6.4 rebounds, while Jalen Duren is averaging 19.5 points and 2 assists. Tobias Harris is the third double-digit scorer and Duncan Robinson is grabbing 2.9 rebounds. The Detroit Pistons are shooting 35.9 percent from beyond the arc and 74.6 percent from the free-throw line. The Detroit Pistons are allowing 36.7 percent shooting from deep and are grabbing 46.4 rebounds per game.
Why the Detroit Pistons will win
- The Pistons have won each of their last eight Friday games against Northwest Division opponents that held a losing record.
- The Trail Blazers have lost 10 of their last 11 games against Eastern Conference opponents that held a winning record.
- The Pistons have covered the spread in each of their last eight Friday games against Northwest Division opponents that held a losing record.
- The Trail Blazers have failed to cover the spread in each of their last five games following a win.
Why the Portland Trail Blazers will win
- The Pistons have lost seven of their last eight games as home favorites against Northwest Division opponents following a loss.
- The underdogs have won four of the Pistons’ last five games.
- The Trail Blazers have covered the spread in each of their last 13 road games against Central Division opponents.
- The Pistons have failed to cover the spread in seven of their last eight home games on the first leg of a back-to-back against Western Conference opponents.
Total Points Facts
- Each of the Pistons’ last four games as favorites have gone UNDER the total points line.
- Each of the Trail Blazers’ last four games against Central Division opponents have gone UNDER the total points line.
Detroit Pistons Player Facts
- Cade Cunningham is one of only two players to have recorded a 40+ point triple-double this season.
- Jalen Duren is one of only three players to have recorded a 20-point, 20-rebound game this season.
Portland Trail Blazers Player Facts
- Shaedon Sharpe ranks 7th amongst qualified players for fast break points per game (4.2) this season.
- Deni Avdija is one of only eight qualified players in the league averaging at least 25.0 points, 5.0 rebounds and 5.0 assists this season.
Matchup/League Facts
- The Pistons rank 1st in the league for opponent assists per game this season (23.4).
- The Pistons rank 1st for points in the paint (1266) this season.
- The Trail Blazers have recorded the largest comeback win from a Q1 deficit this season – trailed by 20 points vs Thunder on November 5.
- The Trail Blazers rank 2nd in the league for offensive rebounds per game this season (14.8).
Pistons vs Trail Blazers Injury Report
The Pistons will be without Bobi Klintman. Duncan Robinson and Marcus Sasser are questionable.
The Trail Blazers will be without Damian Lillard, Blake Wesley, Jrue Holiday, Matisse Thybulle, and Scoot Henderson. Donovan Clingan, Robert Williams III, and Kris Murray are questionable.
Pistons vs Trail Blazers Prediction
The Pistons have cooled off lately, and they’ve failed to cover 5 of their last 6 games. However, the Trail Blazers are tough to get behind with such an injury report. The Trail Blazers have more than half their roster banged up. Not ideal when going up against a defensive feisty Pistons team where depth is the one thing that can counter such pressure. Even with failed covers lately, the Pistons are still a profitable 13-9 ATS on the season. The Trail Blazers need to get guys back before they become attractive again. I’ll lay the points with Detroit basketball.