Cardinals vs Tigers Prediction 4/5/26 MLB Picks Today

In this article, we will formulate a Cardinals vs Tigers Prediction for this MLB matchup on Sunday, April 5^th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Detroit Tigers Preview

The Detroit Tigers have a 4-4 record this season and are sitting in the third place of the AL Central. They have a 2-0 home record and are coming off an 11-6 home win against the Cardinals. Their previous three games were a 4-0 home win against the Cardinals, and a 0-1 road loss and a 5-7 road loss against the Diamondbacks.

The Tigers have a .247 batting average this season, .329 OBP and .384 Slugging percentage. Detroit’s pitching staff has a 3.61 ERA and 1.28 WHIP. Colt Keith is the team’s best hitter with a .417 batting average. Dillon Dingler leads the team in RBI with 7, also adding a team-high two home runs.

Keider Montero (R) is the projected starting pitcher for the Tigers and last season he had a 6-6 record, 4.76 ERA and 1.33 WHIP.

St. Louis Cardinals Preview

The St. Louis Cardinals have a 4-4 record this season and are sitting in the fourth place of the NL Central. They have a 0-2 road record and are coming off a 6-11 road loss against the Tigers. Their previous three games were a 0-4 road loss against the Tigers, and a 2-1 home win and a 3-0 home win against the Mets.

The Cardinals have a .220 batting average this season, .299 OBP and .352 Slugging percentage. St. Louis’ pitching staff has a 5.18 ERA and 1.58 WHIP. Victor Scott II is the team’s best hitter with a .308 batting average. Jordan Walker leads the team in RBI with 8, and Nolan Gorman adds a team-high two home runs.

Kyle Leahy (R) is the projected starting pitcher for the Cardinals, and he has a 0-1 record, 7.20 ERA and 2.00 WHIP.

St. Louis Cardinals @ Detroit Tigers Betting Trends: April 5, 2026

• Probable Starting Pitcher: Keider Montero      Record this season: –      ERA: –
• Home Record: –
• Last 5 against Cardinals: 0-0

Why the Detroit Tigers will win

• The Cardinals have lost each of their last seven road games against American League opponents.
• The home team has won each of the Tigers’ last six games.
• The Cardinals have failed to cover the run line in each of their last seven road games against American League opponents.
• The home team has covered the run line in each of the Tigers’ last six games.
• The Cardinals have lost the first inning in four of their last five night games against AL Central opponents.
• The Tigers have led after 3 innings in four of their last five night games against the Cardinals.
• The Cardinals have trailed after 5 innings in each of their last seven road games.

• Probable Starting Pitcher: Kyle Leahy      Record this season: 0-1      ERA: 7.20
• Road Record: 0-0
• Last 5 against Tigers: 0-2

Why the St. Louis Cardinals will win

• The Tigers have lost eight of their last nine games as favorites after playing the previous day.
• The Cardinals have won five of their last six games as underdogs against AL Central opponents following a loss.
• The Tigers have failed to cover the run line in eight of their last nine games as favorites after playing the previous day.
• The Cardinals have covered the run line in five of their last six games as underdogs against AL Central opponents following a loss.
• The Tigers have trailed after 3 innings in each of their last four night games against NL Central opponents.
• The Tigers have trailed after 5 innings in seven of their last eight night games against National League opponents.

Total Runs Facts

• Seven of the Tigers’ last eight home games against NL Central opponents have gone OVER the total runs line.
• Five of the Cardinals’ last six night games against AL Central opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Tigers’ last nine night games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Cardinals’ last six night games against AL Central opponents.

Detroit Tigers Player Prop Facts

• Matt Vierling has hit a home run in each of his last two appearances against the Cardinals.
• Jake Rogers has recorded at least one hit in each of his last 10 home appearances against NL Central opponents.
• Colt Keith ranks 5th amongst qualified players for Batting Average (.417) this season.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has hit a home run in four of his last eight road appearances against AL Central opponents.
• Alec Burleson has recorded at least one hit in each of his last nine road appearances against AL Central opponents.

Matchup/League Facts

• The Tigers rank T4th in the league for triples this season (2).
• The Tigers rank T5th in the league for doubles this season (14).
• The Cardinals rank 30th in the league for strikeouts this season (47).
• The Cardinals rank 30th in the league for hits allowed this season (81).

Cardinals vs Tigers Prediction

The Tigers are 6-1 in their last 7 meetings against the Cardinals, having won their last four meetings in Detroit.

In this Cardinals vs Tigers Prediction, the Tigers are coming as -140 home favorites. The Tigers have been dominating the Cardinals in this series, having won both games with a combined 15-6 score, but I’m not rushing to back Montero as a starter, as he had been shaky last season and weaker at home with a 4.85 ERA. The Cardinals are starting with a reliever and have the 8^th-worst bullpen ERA in baseball, so I don’t trust either side and I will take the over 8 runs in this one.