Cleveland Cavaliers (49-29) vs. Memphis Grizzlies (25-53)
April 6, 2026 8:00 pm EDT
The Line: Memphis Grizzlies +13.5; Over/Under: 237.5
(Get latest betting odds)
The Memphis Grizzlies play host to the Cleveland Cavaliers at the FedExForum on Monday night. Here’s a Grizzlies vs. Cavaliers Prediction. This article will include a Grizzlies vs. Cavaliers Pick.
Cleveland Cavaliers Betting Preview
The Cleveland Cavaliers have been on a tear as they’ve reeled off eight wins from their past 10 games overall and they will be aiming for a third straight victory after beating the Pacers in a 117-108 home win last night. Donovan Mitchell led the team with 38 points, six rebounds and six assists; James Harden added 28 points with seven assists, while Thomas Bryant chipped in with 14 points and 10 rebounds. As a team, the Cavaliers shot 47 percent from the field and 16 of 47 from the 3-point line as they got off to a sluggish start and found themselves in a real arm wrestle with the pesky Pacers until the fourth quarter, where they went on a decisive 20-5 run to pull ahead and win comfortably in the end.
Memphis Grizzlies Betting Preview
Meanwhile, the Memphis Grizzlies have been doing it tough for a while now, as they’ve dropped 17 of their last 19 games overall and they will be hoping to snap a four-game losing streak after getting trampled by the Bucks in a 131-115 road defeat on Sunday. Rayan Rupert led the team with a triple-double of 33 points with 10 rebounds and 10 assists; Walter Clayton Jr. added 20 points while Dariq Whitehead chipped in with 16 points off the bench. As a team, the Grizzlies shot 41 percent from the field and 17 of 46 from the 3-point line as they struggled to keep pace from the very start and leaked 34 points in the first quarter to fall behind and things only got worse in the fourth quarter, where they leaked another 39 points to lose by double digits in the end.
Why the Memphis Grizzlies will win
- The Cavaliers have lost four of their last five games as favorites following a home win.
- The Grizzlies have won nine of their last 10 home games with both teams on the second leg of a back-to-back.
- The Cavaliers have failed to cover the spread in each of their last 12 games as favorites following a win.
- The home team has covered the spread in each of the Cavaliers’ last five games with both teams on the second leg of a back-to-back.
Why the Cleveland Cavaliers will win
- The Cavaliers have won each of their last 14 night games against Southwest Division opponents that held a losing record.
- The Grizzlies have lost each of their last eight games against teams that held a winning record.
- The Grizzlies have failed to cover the spread in seven of their last eight Monday home games.
- The Cavaliers have covered the spread in six of their last eight road games against the Grizzlies.
Total Points: Facts
- Each of the Grizzlies’ last six games with both teams on the second leg of a back-to-back has gone OVER the total points line.
- Each of the Cavaliers’ last four games as road favorites has gone UNDER the total points line.
Cleveland Cavaliers Player Facts
- James Harden has recorded 65 games with 4+ assists this season—equal to the most of any player in the league.
- Donovan Mitchell is one of only four players in the league to have made 7+ threes in consecutive games this season.
Matchup/League Facts
- Twelve different Grizzlies players have scored 25+ points in a game this season—equal to the most in the league.
- The Grizzlies are one of only two teams to lose 12+ games when leading after Q3 this season.
- The Cavaliers rank 1st in the league for Q4 points per game this season (29.9).
- The Cavaliers rank 1st in the league for H2 points per game this season (61.0).
Grizzlies vs Cavaliers Prediction
The Cavaliers are still missing Evan Mobley, Dean Wade, Jaylon Tyson, Jarrett Allen and Sam Merrill, while the Grizzlies have ruled out seven players already with Cedric Coward, Ty Jerome, Javon Small and GG Jackson all listed as day-to-day. The Cavaliers were always going to be heavy favorites in this matchup given all the injuries the Grizzlies are dealing with, but they have plenty of injuries themselves. It’s hard to picture anything but a comfortable win for the Cavaliers, but they only beat the Grizzlies by eight points in their last meeting and I think we’re about to see a similar outcome. Give me the Cavaliers to get the win on the road, but for the Grizzlies to hang around long enough to get the cover.
