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Cardinals vs Reds Prediction 6/7/26 MLB Picks Today

Cincinnati Reds (31-32) vs. St. Louis Cardinals (34-28)
June 7, 2026 2:15 pm EDT
The Line: St. Louis Cardinals -136 / Cincinnati Reds 113; Over/Under: 9
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In this article we will formulate a Cardinals vs Reds prediction for this MLB game on Sunday, June 7th at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 34-28 this season after they won the first two games in this series by scores of 10-3 and 6-5. In game two, St. Louis trailed 5-3 in the fourth, but they scored the last three runs to get the win. The Cardinals recorded 12 hits and they committed one error, while they were led by Nootbaar, who went 1-1 with one home run and two RBIs in the game. Liberatore allowed four hits and three earned runs over 4.1 innings, while Soriano got the win and O’Brien picked up the save. Prior to this series, St. Louis lost two out of three against the Rangers, but did win two out of three against the Cubs before that. 


This season, St. Louis has a 4.11 ERA with a 1.36 WHIP and a .254 opponent batting average, while they have scored 273 runs with a .243 batting average and a .321 on base percentage. Jordan Walker has led the Cardinals with 16 home runs and 46 RBIs, while Alec Burleson has added eight home runs and 43 RBIs. The projected starting pitcher for St. Louis is Michael McGreevy, who is 3-5 with a 2.98 ERA and a 1.10 WHIP over 66.1 innings pitched this season. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 31-32 this year after they lost game two by a score of 5-6 on Saturday afternoon. Cincinnati led 5-3 in the fourth inning and they had a great chance to tie the game late, but fell short in the loss. The Reds recorded nine hits and they committed one error in the game, while they were led by McLain, who went 1-3 with one home run and two RBIs. Lodolo allowed nine hits and four earned runs over 5.0 innings, while Moll allowed two earned runs for the loss. Prior to this series, Cincinnati lost two out of three against the Royals and two out of three against the Braves. 

This season, Cincinnati has a 4.83 ERA with a 1.47 WHIP and a .251 opponent batting average, while they have scored 272 runs with a .230 batting average and a .313 on base percentage. Elly De La Cruz has led the Reds with 12 home runs and 37 RBIs, while Sal Stewart has added 12 home runs and 39 RBIs. The projected starting pitcher for Cincinnati is Rhett Lowder, who is 3-3 with a 5.40 ERA and a 1.41 WHIP over 38.1 innings pitched this year. 

Why the St. Louis Cardinals will win

  • The Reds have lost each of their last 10 road games against NL Central opponents.
  • The favorites have won each of the Cardinals’ last seven games.
  • The Reds have failed to cover the run line in four of their last five games.
  • The Cardinals have covered the run line in three of their last four games as favorites.
  • The Cardinals have led after 3 innings in three of their last four day games against opponents that held a losing record.
  • The Cardinals have led after 5 innings in three of their last four games as favorites.

Why the Cincinnati Reds will win

  • The Cardinals have lost 13 of their last 18 games as favorites against National League opponents following a win.
  • The Reds have won six of their last seven Sunday games as underdogs against the Cardinals.
  • The Cardinals have failed to cover the run line in 14 of their last 15 games as favorites against National League opponents following a home win.
  • The Reds have covered the run line in each of their last six day games against the Cardinals following a loss.
  • The Cardinals have trailed after 5 innings in each of their last four day games at Busch Stadium against National League opponents.

Total Runs Facts

  • Each of the Cardinals’ last five games as favorites against the Reds have gone OVER the total runs line.
  • Each of the Reds’ last five games as underdogs against NL Central opponents have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of Michael McGreevy’s last eight appearances as a starter.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Reds’ last four day games against NL Central opponents.

St. Louis Cardinals Player Prop Facts

  • Alec Burleson has hit a home run in two of the Cardinals’ last three home games against the Reds.
  • Masyn Winn has recorded at least one hit in each of his last six home appearances against the Reds after playing the previous day.
  • Jordan Walker is one of only three players to hit over .300 and have 45+ RBIs this season.

Cincinnati Reds Player Prop Facts

  • JJ Bleday has recorded at least one hit in each of the Reds’ last eight road games against NL Central opponents.
  • Elly De La Cruz has hit a home run in two of his last three appearances with the Reds as underdogs against the Cardinals.
  • Sal Stewart is one of only nine players to record 10+ Home Runs and 10+ Stolen Bases this season.

Matchup/League Facts

  • The Cardinals rank T27th in the league for triples this season (5).
  • The Cardinals rank 27th in the league for strikeouts this season (478).
  • The Reds rank 28th in the league for ERA this season (4.83).
  • The Reds rank 28th in the league for walks allowed this season (290).

Cardinals vs Reds Prediction 

St. Louis comes into this matchup on a three game winning streak and they have scored 25 runs in their last four games. The Cardinals are 18-16 at home this year, while the Reds are 15-16 on the road. Cincinnati has lost three in a row and they have scored three runs or fewer in three of their last five. The Reds are starting Lowder, who is coming off of the IL, while McGreevy has allowed 2, 5, 3, 1, and 0 earned runs in his last five starts. Take the Cardinals at home here. 

David Racey's Free Pick: Cardinals ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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