Yankees vs Diamondbacks Prediction 9/19/26 MLB Picks Today
NY Yankees (89-64) vs. Arizona Diamondbacks (80-74)
September 19, 2026 8:10 pm EDT
The Line: Arizona Diamondbacks 122 / NY Yankees -148; Over/Under: 7.5
(Get latest betting odds)
In this article, we will formulate a Yankees vs Diamondbacks Prediction for this MLB matchup on Saturday, September 19th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.
Arizona Diamondbacks Preview
The Arizona Diamondbacks have a 80-74 record this season and are sitting in the 3rd place of the NL West. They have a 43-36 home record and are coming off a 2-9 home loss against the Yankees. They will face the Rockies and the Padres next.
The Arizona Diamondbacks have a .243 batting average this season, .315 OBP and .397 Slugging percentage. Arizona’s pitching staff has a 4.11 ERA and 1.28 WHIP. Gabriel Moreno is the team’s best hitter with a .304 batting average, adding a team-high 75 RBI. Nolan Arenado adds a team-high 26 home runs.
Brandon Pfaadt (R) is the projected starting pitcher for the Diamondbacks, and he has a 7-3 record, 3.77 ERA and 1.17 WHIP.
New York Yankees Preview
The New York Yankees have a 89-64 record this season and are sitting in the 2nd place of the AL East. They have a 47-32 away record and are coming off a 9-2 road win against the Diamondbacks. They will face the Rays and the Orioles next.
The New York Yankees have a .235 batting average this season, .312 OBP and .410 Slugging percentage. New York’s pitching staff has a 3.18 ERA and 1.16 WHIP. Cody Bellinger is the team’s best hitter with a .275 batting average. Ben Rice leads the team in RBI with 94, adding a team-high 39 home runs.
Cam Schlittler (R) is the projected starting pitcher for the Yankees, and he has a 14-6 record, 1.95 ERA and 0.90 WHIP.
New York Yankees @ Arizona Diamondbacks Betting Trends: September 19, 2026
- Probable Starting Pitcher: Brandon Pfaadt Record this season: 7-3 ERA: 3.77
- Home Record: 3-2
- Last 5 against Yankees: 0-1
Why the Arizona Diamondbacks will win
- The Diamondbacks have won eight of their last nine games as underdogs following a home loss.
- The Yankees have lost each of their last five games against NL opponents following a road win.
- The underdogs have covered the run line in 11 of the Diamondbacks’ last 12 games.
- The Yankees have failed to cover the run line in each of their last four night games against NL opponents following a road win.
- The Diamondbacks have led after 3 innings in five of their last six home games against AL opponents that held a winning record.
- The Diamondbacks have led after 5 innings in eight of their last nine night games at Chase Field against AL East opponents.
- Probable Starting Pitcher: Cam Schlittler Record this season: 14-6 ERA: 1.95
- Road Record: 8-2
- Last 5 against Diamondbacks: –
Why the New York Yankees will win
- The Yankees have won each of their last seven night games after playing the previous day.
- The Diamondbacks have lost seven of their last eight games against AL East opponents.
- The Diamondbacks have failed to cover the run line in each of their last six games.
- The Yankees have covered the run line in each of their last six games against NL West opponents.
- The Yankees have won the first inning in four of their last five games against NL opponents.
- The Diamondbacks have trailed after 3 innings in each of their last seven night games against AL opponents that held a winning record.
- The Diamondbacks have trailed after 5 innings in each of their last nine night games against opponents that held a winning record.
Total Runs Facts
- Eight of the Yankees’ last nine night games after playing the previous day have gone OVER the total runs line.
- Seven of the Diamondbacks’ last eight games as underdogs have gone UNDER the total runs line.
- There has been no run scored during the first inning in each of Brandon Pfaadt’s last six home appearances as a starter.
- There has been at least one run scored in the first inning in seven of the Yankees’ last eight games.
Arizona Diamondbacks Player Prop Facts
- Ketel Marte has hit a home run in each of his last two appearances with the Diamondbacks as underdogs against AL East opponents.
- Brandon Pfaadt has recorded a win in three of his last four home appearances against AL East opponents.
- Brandon Pfaadt has recorded five or more strikeouts in each of his last three home appearances against AL opponents that held a winning record.
- Nolan Arenado has recorded at least one hit in each of his last 16 appearances against the Yankees.
- Gabriel Moreno ranks 6th amongst qualified players for Batting Average (.304) this season.
New York Yankees Player Prop Facts
- Cam Schlittler has recorded a win in four of his last five appearances.
- Cam Schlittler has recorded seven or more strikeouts in seven of his last eight road appearances.
- Ryan McMahon has recorded at least one hit in each of his last 15 appearances with his team as a favorite against the Diamondbacks.
- Aaron Judge has hit at least one home run in four of his last five appearances with the Yankees as road favorites against NL West opponents.
- Cam Schlittler ranks 2nd amongst qualified players for Earned Run Average (1.95) this season.
Matchup/League Facts
- The Diamondbacks rank 2nd in the league for triples this season (36).
- The Diamondbacks rank 29th in the league for strikeouts this season (1080).
- The Yankees rank 1st in the league for ERA this season (3.18).
- The Yankees rank 1st in the league for runs allowed this season (563).
Yankees vs Diamondbacks Prediction
Both teams are tied 3-3 in their last 6 meetings and the Yankees are 3-1 in their last 4 visits in Arizona.
In this Yankees vs Diamondbacks Prediction, the Yankees are coming as -140 road favorites. We are getting the Yankees in a discount prize, with the red-hot Cam Schlittler on the mound, who has not given up more than one run across his last seven starts and has been one of the best road pitchers in baseball. On the flip side, Brandon Pfaadt is starting to look like the last season’s version of himself, with 12 earned runs across his last three home starts. The Yankees also have the best bullpen in baseball, so take them on the moneyline in this one.