Dodgers vs Padres Prediction 9/23/26 MLB Picks Today
San Diego Padres (87-70) vs. LA Dodgers (97-60)
September 23, 2026 10:10 pm EDT
The Line: LA Dodgers -224 / San Diego Padres 182; Over/Under: 8
(Get latest betting odds)
The San Diego Padres and Los Angeles Dodgers meet Wednesday in MLB action at Dodger Stadium. Here’s a Dodgers vs. Padres Prediction. This article will include a Dodgers vs. Padres Pick.
San Diego Padres Betting Preview
The San Diego Padres are 87-70 on the year and play the Diamondbacks next. The San Diego Padres are batting .243 on the season, have a .318 OBP, and have a .398 slugging percentage. The San Diego Padres’ pitching staff has a 3.96 ERA and a 1.29 WHIP. Fernando Tatis Jr. leads the San Diego Padres with 173 hits and 81 RBI, while Jackson Merrill and Ty France have combined for 278 hits and 156 RBI.
Robbie Ray gets the ball for the San Diego Padres, and he is 13-8 with a 3.60 ERA and 138 strikeouts this season. Ray is 9-9 with a 3.81 ERA and 191 strikeouts in his career against the Los Angeles Dodgers.
Los Angeles Dodgers Betting Preview
The Los Angeles Dodgers are 97-60 this year and play the Giants next. The Los Angeles Dodgers are batting .257 on the season, with a .339 OBP and a .426 slugging percentage. The Los Angeles Dodgers’ pitching staff has a 3.59 ERA and a 1.15 WHIP. Freddie Freeman leads the Los Angeles Dodgers with 165 hits and 70 RBI, while Andy Pages and Shohei Ohtani have combined for 273 hits and 160 RBI.
Yoshinobu Yamamoto gets the ball for the Los Angeles Dodgers, and he is 14-8 with a 2.51 ERA and 178 strikeouts this season. Yamamoto is 3-3 with a 3.76 ERA and 41 strikeouts in his career against the San Diego Padres.
Why the Los Angeles Dodgers will win
- The Dodgers have won each of their last 11 home games.
- The Padres have lost seven of their last eight games at UNIQLO Field at Dodger Stadium.
- The Dodgers have covered the run line in seven of their last eight games.
- The Padres have failed to cover the run line each of their last three games against teams that held a winning record.
- The Dodgers have led after 5 innings in each of their last six home games against NL West opponents that held a winning record.
- The Padres have trailed after 3 innings in six of their last seven games as road underdogs.
Why the San Diego Padres will win
- The Padres have won each of their last nine night games following a road loss.
- The Dodgers have lost five of their last six games against teams that held a winning record.
- The Padres have covered the run line in each of their last nine games as underdogs following a loss.
- The Dodgers have failed to cover the run line in four of their last five games against NL West opponents that held a winning record.
- The Dodgers have lost the first inning in three of their last four games against opponents that held a winning record.
- The Padres have led after 5 innings in eight of their last nine games against NL West opponents.
Total Runs Facts
- Each of the Padres’ last six night games after playing the previous day have gone OVER the total runs line.
- Each of the last four games between the Padres and Dodgers have gone UNDER the total runs line.
- There has been at least one run scored in the first inning in nine of the Padres’ last 10 road games.
- There has been at least one run scored in the first inning in four of the Dodgers’ last five games.
Los Angeles Dodgers Player Prop Facts
- Will Smith has hit a home run in each of the Dodgers’ last three night games.
- Yoshinobu Yamamoto has recorded seven or more strikeouts in each of his last six appearances.
- Teoscar Hernandez has recorded at least one hit in each of the Dodgers’ last 13 home games.
- Yoshinobu Yamamoto has recorded a win in three of his last four appearances against the Padres.
- Yoshinobu Yamamoto ranks 5th amongst qualified players for Earned Run Average (2.51) this season.
San Diego Padres Player Prop Facts
- Fernando Tatis Jr. has hit a home run in two of the Padres’ last three games.
- Samad Taylor has recorded at least one hit in each of his last eight appearances after playing the previous day.
- Robbie Ray has recorded four or more strikeouts in each of his last 10 road appearances.
- Robbie Ray has recorded a win in each of his last seven road appearances against NL opponents.
- Fernando Tatis Jr. ranks T4th in the league in Hits (174) this season.
Matchup/League Facts
- The Dodgers rank 1st in the league for opponent batting average this season (.219).
- The Dodgers rank 1st in the league for hits allowed this season (1128).
- The Padres rank 5th in the league for steals this season (157).
- The Padres rank 24th in the league for doubles this season (228).
Dodgers vs Padres Prediction
This price is nuts when you consider the Padres are the hottest team in the league. As good as Yamamoto is, Ray has found his All-Star form and is rocking a 3.60 ERA and 1.33 WHIP. He was brought to San Diego for spots like this. With all of that said, the Dodgers are putting together a strong week, and all of a sudden have put themselves in position to snag the top overall seed for the playoffs. We know what the Dodgers do this time of year. The Padres are known for tripping over themselves. I’ll roll with the Dodgers and the RL for max betting value.