Clemson vs South Carolina Prediction 12/16/25 College Basketball Picks Today

In this article we will formulate a Clemson vs South Carolina prediction for this College Basketball game on Tuesday, December 16th at the Littlejohn Coliseum in Clemson, South Carolina. Let’s take a look at the prediction for this College Basketball matchup.

Clemson Tigers Betting Preview

The Clemson Tigers are 8-3 this year after they defeated Mercer by a score of 70-63 in their last game. Clemson trailed 39-33 at halftime, but outscored Mercer 37-24 in the second half for the win. The Tigers shot 46% from the field, 31% on three pointers, and 75% on free throws in the game. Dillon Hunter led Clemson with 15 points and two assists, while Nick Davidson added 12 points and five rebounds in the win. 

Prior to that game, Clemson lost to BYU by a score of 67-64 and Alabama by a score of 90-84. The Tigers have scored 81.8 points per game with 41.4 rebounds and 15.2 assists per game, while they have allowed 66.4 points against per game this season. RJ Godfrey is averaging 11.9 points and 6.5 rebounds per game, while Jestin Porter is averaging 10.8 points and 2.3 rebounds per game for the Tigers. Clemson is shooting 45.5% from the field, 75.6% on free throws, and 32.4% on three pointers this year. 

South Carolina Gamecocks Betting Preview

The South Carolina Gamecocks are 7-3 this season after they defeated The Citadel by a score of 71-55 in their last game. South Carolina led 35-28 at halftime and held The Citadel to 27 points in the second half in the win. The Gamecocks shot 42% from the field, 13% on three pointers, and 86% on free throws in the game. Meechie Johnson led South Carolina with 19 points and three assists, while Mike Sharavjamts added 14 points and seven rebounds in the win. 

Prior to that game, South Carolina defeated Stetson by a score of 82-51, but lost to Virginia Tech by a score of 86-83 before that. The Gamecocks have scored 80.1 points per game with 36.2 rebounds and 15.4 assists per game, while they have allowed 68.2 points against per game this season. Meechie Johnson is averaging 15.5 points and 3.4 assists per game, while Mike Sharavjamts is averaging 11.6 points and 6.6 rebounds per game for the Gamecocks. South Carolina is shooting 45.7% from the field, 76.9% on free throws, and 31.3% on three pointers this season. 

Why the Clemson Tigers will win

• Clemson has won each of its last 16 night games against non-Conference opponents at Littlejohn Coliseum.
• South Carolina has lost each of its last three games at Littlejohn Coliseum following a home win.
• Clemson has won the first half in each of its last 13 night games against non-Conference opponents at Littlejohn Coliseum.

Why the South Carolina Gamecocks will win

• South Carolina has won nine of its last 10 night games against non-Conference opponents.
• Clemson has lost three of its last four night games against the Southeastern Conference.
• South Carolina has won the first half in 25 of its last 27 night games against non-Conference opponents.

Total Points Facts

• Each of South Carolina’s last six road games against the Atlantic Coast Conference have produced a total of 139 or fewer points.
• Four of Clemson’s last five games against the Southeastern Conference have produced a total of 171+ points.

Clemson vs South Carolina Prediction 

Clemson comes into this matchup after losing two of their last three games and they nearly lost to Mercer in their last game, but they are 6-0 at home. The Tigers are shooting 45% from the field this year and they have allowed 67 points or fewer in three of their last four. South Carolina has won three of their last four games, but this is their first road game. The Gamecocks are shooting 46% from the field and they have allowed 62 points or fewer in three of their last four. I think we are going to see a defensive battle in this matchup, so I like the under here.