Louisville vs Clemson Prediction 3/14/25 College Basketball Picks Today
Clemson (27-5) vs. Louisville (26-6)
March 14, 2025 9:30 pm EDT
The Line: Louisville +1; Over/Under: 141.5
(Get latest betting odds)
The Louisville Cardinals and the Clemson Tigers meet Friday in college basketball action from the Spectrum Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Louisville vs. Clemson prediction.
Matchup History
The Louisville Cardinals won the lone meeting between these two teams back on January 7th, 2025, by a final score of 74-64 at home.
Louisville Recap
The Louisville Cardinals come into this one fresh off of a 75-73 win over Stanford in their last game to punch their ticket to the conference semi-finals.
Cardinals Hunting For First ACC Tournament Title
Chucky Hepburn leads the Cardinals in scoring and assists with 16.4 PPG and 5.9 APG along with 3.5 RPG and 2.4 SPG while Reyne Smith has 13.4 PPG with 2.8 RPG this season. Terrence Edwards Jr. has 16.1 PPG with 3.9 RPG and 2.6 APG and J’Vonne Hadley also has 12.1 PPG with a team-high 7.3 RPG to lead the Cardinals on the glass, also rounding out the group of double-digit scorers for Louisville so far this season. James Scott has also chipped in 7.3 PPG with 6.4 RPG as well on the year. As a team, Louisville is averaging 79.2 PPG on 45.7% shooting from the field, 33.3% from three and 74.5% from the foul line this season.
Why the Louisville Cardinals will win
- Louisville has won each of its last 12 night games.
- Clemson has lost six of its last eight games against AP-ranked opponents at a neutral venue.
Clemson Recap
The Clemson Tigers come into this game after picking up a 57-54 win over SMU last time out to book their spot in the tournament semis.
Tigers Looking For First ACC Title Game Appearance Since 2008
Chase Hunter leads Clemson in scoring with a team-high 16.2 PPG with 3 RPG and 2.5 APG while Viktor Lakhin has 11.5 PPG with 6.3 RPG. Ian Schieffelin has 12.8 PPG with a team-high 9.3 RPG and 2.8 APG to lead the Tigers in rebounding. Jaeden Zackary also has 11.3 PPG with a team-high 3.2 APG to lead Clemson in assists, while also capping off the group of double-digit scorers for Clemson so far this season. Chauncey Wiggins also has 8.3 PPG with 3 RPG as well this season. As a team, Clemson is averaging 76.4 PPG on 46.8% shooting from the field, 37.3% from three and 76.4% from the foul line this season.
Why the Clemson Tigers will win
- Louisville has lost each of its last 11 night games against AP-ranked opponents.
- Clemson has won each of its last nine games.
Total Points Facts
- Nine of Clemson’s last 10 Conference Tournament games have produced a total of 134 or fewer points.
- Each of Louisville’s last four night games against Top 10 AP-ranked opponents at a neutral venue have produced a total of 147+ points.
Louisville vs Clemson Prediction
I’m on Clemson here. I think this is a tricky revenge spot for Clemson to get even with Louisville. While I was on both of these teams on Thursday and got nipped in the ATS department, I still think that Clemson will be able to slow down Louisville here. Against the Cardinals, you have to be able to defend the three, and I think Clemson can do that, and I also think that the Tigers are the more complete team side-by-side. I’ll take Clemson in this one.
