Oklahoma State vs Iowa State Prediction 2/25/25 College Basketball Picks Today

The Iowa State Cyclones and the Oklahoma State Cowboys meet Tuesday in college basketball action from Gallagher-Iba Arena. Here’s an Oklahoma State vs Iowa State prediction. We will look at this from a betting perspective and determine the best Oklahoma State vs Iowa State pick.

Iowa State Cyclones Betting Preview

The Cyclones have really only had one spotty run so far this year. Otherwise, they’ve been rattling off wins at a very nice rate. Following a loss to Auburn in their fourth game of the season, Iowa State posted victories versus Dayton, Colorado, Marquette, Jackson State, Iowa, Omaha, Morgan State, Colorado, Baylor, Utah, Texas Tech, and Kansas in the next dozen outings. A 2-4 stretch came next with wins over UCF and Arizona State among losses to West Virginia, Arizona, Kansas State, and Kansas. The next four were victories over TCU, UCF, Cincinnati, and Colorado though, giving the Cyclones a 21-5 record through 26 games.

In their Saturday matchup with Houston, Iowa State went into the locker room trailing significantly 34-22. The Cyclones got slightly better from there on a 37-34 run but still lost handily 68-59. Milan Momcilovic led the team with 16 points, five rebounds, one assist, and one steal in 35 minutes. Nate Heise put up 12 points with two rebounds in the losing effort, and Tamin Lipsey had 11 points with two assists and two steals in 34 minutes of work out there.

Oklahoma State Cowboys Betting Preview

Over on the Oklahoma State side, they started out pretty well but they’ve been on a rough run since late December. The Cowboys took out Green Bay, St. Thomas MN, Southern Illinois, Miami, Tulsa, Seton Hall, Tarleton State, and Oral Roberts during an 8-3 stretch across their first 11 outings. Oklahoma State would go a rough 5-10 over the next 15 games though, beating only Kansas State, Colorado, Utah, Arizona State, and UCF. The losses otherwise were versus Houston, West Virginia, Utah, BYU, Arizona, Texas Tech, Kansas State, Houston, TCU, and Texas Tech in succession, giving the Cowboys a .500 record through 26 games at 13-13.

Matched up against Kansas this past weekend, the Cowboys were blitzed 52-23 in the first half. Things got better on a 44-41 deficit from there but Oklahoma State still lost significantly 96-64. Bryce Thompson was the team’s leading player with 21 points, four rebounds, two assists, and two steals. Brandon Newman came off the bench for 11 points with two rebounds and two steals, while Marchelus Avery had 10 points with three rebounds, three steals and two assists in 18 minutes of bench work. Leading among the rest of the starters was Abou Ousmane with seven points, two steals, one rebound, and one assist in 19 minutes.

Why the Oklahoma State Cowboys will win

• The home team has won eight of Oklahoma State’s last nine games.
• Iowa State has lost three of its last four road games.
• The home team has won the first half in eight of Oklahoma State’s last nine games.

Why the Iowa State Cyclones will win

• Oklahoma State has lost each of its last 20 night games against AP-ranked opponents.
• Iowa State has won 19 of its last 20 night games against non-AP-ranked opponents.
• Oklahoma State has lost the first half in each of its last 12 night games against AP-ranked opponents.

Oklahoma State vs Iowa State Prediction

I’ll lean toward Iowa State. The Cyclones need a good bounce-back effort here following a pretty listless loss to a talented Houston team, though. In that one, Iowa State shot just 39.1 percent from the field with a 29-22 rebounding deficit and 12 turnovers for 16 Cougars points. The Cyclones gave up 53.2 percent shooting on the other side overall and 58.8 percent (10-of-17) from 3-point range. The loss snaps a four-game win streak and the 59 points mark Iowa State’s lowest total since scoring just 52 in a road loss to Kansas on February 3.

As for Oklahoma State, they had a tough road matchup versus Kansas over the weekend themselves. The Cowboys shot just 36.7 percent from the field versus the Jayhawks’ 52.1 percent and had a 48-28 rebounding deficit. The 17 turnovers for 27 Kansas points didn’t help matters either, though it was a pretty sloppy game overall for ball control. Oklahoma State is currently sitting on a 1-3 stretch with fewer than 65 points in consecutive losses. Iowa State has a good opportunity to assert themselves at home here and power out a cover.