Purdue vs Iowa State Prediction 12/6/25 College Basketball Picks Today

The Iowa State Cyclones and Purdue Boilermakers meet Saturday in the college basketball action at the Mackey Arena. Here’s a Purdue vs Iowa State Prediction. This article will include a Purdue vs Iowa State Pick.

Iowa State Cyclones Betting Preview

The Iowa State Cyclones beat Syracuse and Alcorn State, and they play Iowa next. Iowa State has won 8 straight games.

The Iowa State Cyclones are averaging 96.3 points on 55 percent shooting and allowing 74.9 points on 42.1 percent shooting. Tamin Lipsey is averaging 18.4 points and 5.2 assists, while Joshua Jefferson is averaging 18.4 points and 7.3 rebounds. Milan Momcilovic is the third double-digit scorer and Killyan Toure is grabbing 2.6 rebounds. The Iowa State Cyclones are shooting 43.3 percent from beyond the arc and 69.5 percent from the free throw line. The Iowa State Cyclones are allowing 34 percent shooting from deep and are grabbing 37.3 rebounds per game.

Purdue Boilermakers Betting Preview

The Purdue Boilermakers beat Eastern Illinois and Rutgers, and they play Minnesota next. Purdue has won 8 straight games.

The Purdue Boilermakers are averaging 88.6 points on 51 percent shooting and allowing 64 points on 40.2 percent shooting. Fletcher Loyer is averaging 15.6 points and 2.4 rebounds, while Trey Kaufman-Renn is averaging 15.5 points and 11 rebounds. Braden Smith is the third double-digit scorer and Oscar Cluff is grabbing 9.3 rebounds. The Purdue Boilermakers are shooting 41.9 percent from beyond the arc and 77.3 percent from the free throw line. The Purdue Boilermakers are allowing 30.6 percent shooting from deep and are grabbing 43.6 rebounds per game.

Why the Purdue Boilermakers will win

• Purdue has won each of its last 36 games against non-Conference opponents at Mackey Arena.
• Iowa State has lost six of its last seven day games against Top 5 AP-ranked opponents.
• Purdue has won the first half in each of its last 22 day games against non-Conference opponents at Mackey Arena.

Why the Iowa State Cyclones will win

• Iowa State has won each of its last eight games.
• Purdue has lost three of its last four day games against the Big 12 Conference.
• Iowa State has won the first half in seven of its last eight games.

Total Points Facts

• Twenty-six of Iowa State’s last 29 games against Top 10 AP-ranked opponents have produced a total of 151 or fewer points.
• Each of Purdue’s last four games against AP-ranked opponents at Mackey Arena have produced a total of 155+ points.

Purdue vs Iowa State Prediction

Purdue is the more trustworthy team, and it doesn’t hurt to be at home, but Iowa State enters this contest with a point to prove. Iowa State is unbeaten and 6-2 ATS on the season, led by one of the best offenses in the country. Iowa State has scored in the 80s in 7 of its 8 games this season, and just scored 132 points against Alcorn State. If those shots keep falling, Purdue will have its hands full in this one. I love getting points with an elite offense, as it’s not like Iowa State needs the help. This has a chance to be a high scoring back and forth contest. I want the points in my pocket. Give me the Cyclones.