Syracuse vs Iowa State Prediction 11/26/25 College Basketball Picks Today

In this article, we will formulate a Syracuse vs Iowa State Prediction for this College Basketball game on Wednesday, November 26^th. Let’s take a look at the prediction for this College Basketball matchup.

Iowa State Cyclones Preview

The Cyclones are 6-0 this season and sit 5th in the Big 12. They are 4-2 against the spread, 4-2 in over/under and are 3-0 at home. The Cyclones are coming off a 78-60 victory at home against Creighton. The Cyclones score 90.5 points per game offensively, which is 8th in the country, while allowing 65.2 points per game on defense (55th). Iowa State has a 52% field goal percentage (45th), and a 33.3% 3-point percentage (120th). They have a 77.8% free throw percentage (64th), and average 37.8 boards per game (103rd), and 17.2 dimes per game (33rd) while making 12 turnovers per game (170th).

Tamin Lipsey is the top scorer for the Cyclones, with 18.4 points and 5.2 dimes per game. Joshua Jefferson adds 18.3 points and 8.2 boards per game, while Milan Momcilovic follows with 15.7 points per game.

Syracuse Orange Preview

The Orange are 4-2 this season and sit 6th in the ACC. They are 4-2 against the spread, 2-4 in over/under and are 3-0 at home. The Orange are coming off a 71-60 defeat at home by Kansas. The Orange score 76.7 points per game offensively, which is 202nd in the country, while allowing 60.3 points per game on defense (13th). Syracuse has a 47.0% field goal percentage (107th), and a 27.3% 3-point percentage (330th). They have a 77.8% free throw percentage (64th), and average 37.2 boards per game (103rd) and 15.3 dimes per game (128th) while making 12 turnovers per game (170th).

Donnie Freeman is the top scorer for the Orange with 17.8 points and 5.3 boards per game. Kiyan Anthony adds 12.5 points per game, while Naithan George follows with 10.3 points and 3.5 dimes per game.

Syracuse Orange @ Iowa State Cyclones Betting Trends: November 26, 2025

Why the Iowa State Cyclones will win

• Syracuse has lost each of its last nine day games against AP-ranked opponents.
• Iowa State has won each of its last seven day games against non-Conference opponents.
• Iowa State has won the first half in eight of its last nine games against non-AP-ranked opponents.

Why the Syracuse Orange will win

• Iowa State has lost three of its last four games against the Atlantic Coast Conference.
• Iowa State has lost the first half in each of its last four games against the Atlantic Coast Conference.

Total Points Facts

• Each of Syracuse’s last 13 games against non-Conference opponents at neutral venues have produced a total of 157 or fewer points.
• Each of Iowa State’s last nine day games against non-AP-ranked opponents have produced a total of 151 or fewer points.

Matchup/League Facts

• Iowa State ranks 7th among Division 1 teams for field goals made per game this season (33.5).
• Iowa State ranks 8th among Division 1 teams for opponent turnovers per game this season (18.3).
• Syracuse ranks 365th among Division 1 teams for free throw percentage this season (56.2%).
• Syracuse ranks 3rd among Division 1 teams for opponent field goal percentage this season (34.1%).

Syracuse vs Iowa State Prediction

Iowa State enters this matchup as 9.5-point favorites, and they’ve definitely earned that, as they’re undefeated this season with six wins in six games. Syracuse has lost its only road contest so far and both squads are known for their tough defense, ranking inside the top 55 nationally and allowing a combined total of just about 126 points per game. That has led to the under hitting in five of their last seven combined games, so I’m expecting another tight, low-scoring battle. Take the under 157.5 points in this one.