College Football

Kentucky vs Ole Miss Prediction Football Picks Today 9/6/25

Ole Miss Rebels (1-0) vs. Kentucky Wildcats (1-0)
September 6, 2025 3:30 pm EDT
The Line: Kentucky Wildcats 10 / Ole Miss Rebels -10; Over/Under: 51.5
(Get latest betting odds)

The Ole Miss Rebels and Kentucky Wildcats meet Saturday in college football action at Kroger Field. Here’s a Kentucky vs Ole Miss Prediction. This article will include a Kentucky vs Ole Miss Pick.

Ole Miss Rebels Betting Preview

The Ole Miss Rebels beat Georgia State, and they play Arkansas and Tulane next. The Ole Miss Rebels have won 5 of their last 6 regular season games. Austin Simmons is completing 64.5 percent of his passes for 341 yards, 3 touchdowns, and 2 interceptions. Harrison Wallace III and Dae’Quan Wright have combined for 208 receiving yards and 2 touchdowns, while Caleb Odom has 4 receptions.

The Ole Miss Rebels ground game is averaging 295 yards per contest, and Kewan Lacy leads the way with 108 yards and 3 touchdowns. Defensively, Ole Miss is allowing 7 points and 260 yards per game. TJ Dottery leads the Ole Miss Rebels with 9 tackles, Zxavian Harris has 1 sack and Tahj Chambers has 1 pass deflection.

Kentucky Wildcats Betting Preview

The Kentucky Wildcats beat Toledo, and they play Eastern Michigan and South Carolina next. Kentucky has lost 6 of its last 8 games. Zach Calzada is completing 43.5 percent of his passes for 85 yards, 0 touchdowns, and 1 interception. Josh Kattus and Willie Rodriguez have combined for 74 receiving yards on 5 catches, while Ja’Mori Maclin has 1 reception.

The Kentucky Wildcats ground game is averaging 220 yards per contest, and Dante Dowdell leads the way with 129 yards and 1 touchdown. Defensively, Kentucky is allowing 16 points and 329 yards per game. Alex Afari Jr. leads the Kentucky Wildcats with 13 tackles, Steven Soles Jr. has 2 sacks and Jonquis Hardaway has 1 interception.

Kentucky vs Ole Miss Prediction

Ole Miss is the more talented team, but that didn’t stop Kentucky from upsetting the Rebels last year as 15.5-point underdogs. Kentucky is 7-3 ATS in its last 10 games as a home underdog, and has covered each of its last four games as a double-digit underdog. Ole Miss has failed to cover four of its last seven games as a double-digit favorite, and two of those failed covers were outright losses. Big conference game early in the year, I’ll take a stab with the home dog.

Randy Chambers's Free Pick: Kentucky Wildcats +10

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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