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Louisiana vs South Alabama Prediction 11/1/25 College Football Picks Today

Louisiana vs South Alabama
November 1, 2025 2:30 pm EDT
The Line: South Alabama -4 / Over/Under: 54
(Get latest betting odds)

In this article, we will formulate a Louisiana vs South Alabama Prediction for this College Football Week 10 game on Saturday, November 1st. Let’s take a look at the prediction for this College Football matchup.

South Alabama Jaguars Preview

South Alabama has a 2-6 record this season and is sitting 5th in the Sun Belt. They are 3-5 ATS, 5-3 in Over/Under and have a 1-3 home record and a 1-3 away record. South Alabama is coming off a 38-31 road win against Georgia State and will face Louisiana-Monroe, Southern Mississippi and Texas State next.

Offensively, South Alabama averages 25.2 points per game, ranking 87th in the nation, while defensively, they allow 29.5 points per game, which is 100th. South Alabama averages 378.6 total yards per game (183.3 passing and 195.4 rushing), while allowing 377.4 total yards per game (194.3 rushing and 183.1 passing).

Bishop Davenport leads South Alabama with 1,461 passing yards with 67.0% completed passes and 11 touchdowns. Kentrel Bullock leads the team in rushing yards with 681, while Devin Voisin has a team-high 48 receptions for 642 receiving yards. Defensively, Blayne Myrick has a team-high 53 total tackles (27 of them solo), while Tyler Thomas leads the team in sacks, with 2.0, and Nehemiah Chandler leads the team with 2 interceptions.

Louisiana Ragin’ Cajuns Preview

Louisiana has a 2-6 record this season and is sitting 7th in the Sun Belt. They are 3-5 ATS, 4-4 in Over/Under and have a 2-2 home record and a 0-4 away record. Louisiana is coming off a 23-35 road loss against Troy and will face Texas State, Arkansas State and Louisiana-Monroe next.

Offensively, Louisiana averages 23.5 points per game, ranking 100th in the nation, while defensively, they allow 30.2 points per game, which is 110th. Louisiana averages 336.0 total yards per game (147.1 passing and 188.9 rushing), while allowing 400.0 total yards per game (199.1 rushing and 200.9 passing).

D’Wanyé Winfield leads Louisiana with 671 passing yards with 51.1% completed passes and 5 touchdowns. Zylan Perry leads the team in rushing yards with 487, while Robert Williams has a team-high 16 receptions for 246 receiving yards. Defensively, Jaden Dugger has a team-high 73 total tackles (36 of them solo), while Jordan Lawson leads the team in sacks, with 1.5, and Courtline Flowers leads the team with 2 interceptions.

Louisiana Ragin’ Cajuns @ South Alabama Jaguars Betting Trends: Week 10

 

Why the South Alabama Jaguars will win

  • The home team has won six of Louisiana’s last seven games.
  • Louisiana has lost five of its last six games.
  • South Alabama has covered the spread in four of its last five games against teams from Louisiana.
  • South Alabama has won the first half in six of its last seven games against conference opponents.

Why the Louisiana Ragin’ Cajuns will win

  • South Alabama has lost each of its last three games as a favorite in Alabama.
  • Louisiana has won each of its last four road games against South Alabama.
  • The underdog has covered the spread in seven of the last eight games between Louisiana and South Alabama.
  • South Alabama has failed to cover the spread in each of its last four games as a home favorite.

Total Points Facts

  • Eight of Louisiana’s last nine road games in November have gone OVER the total points line.
  • Each of the last five games between Louisiana and South Alabama have gone UNDER the total points line.

South Alabama Jaguars Player Prop Facts

  • Heading into Week 10, Kentrel Bullock leads the Sun Belt Conference for touchdowns (9) this season.

Louisiana Ragin’ Cajuns Player Prop Facts

  • Heading into Week 10, Tony Sterner leads the Sun Belt Conference for field goals made (12) this season.

Matchup/League Facts

  • South Alabama ranks T135th among FBS teams for 4th down conversion percentage against this season (83.3).
  • South Alabama ranks 133rd among FBS teams for red zone percentage against this season (96.7).
  • Three of Louisiana’s eight games this season have been decided by a margin of three points or less – equal-most amongst FBS teams.
  • Louisiana ranks T134th among FBS teams for Q2 opponent points per game this season (12.5).

Louisiana vs South Alabama Prediction

In their previous meeting last season, South Alabama won 24-22 on the road, but Louisiana is 7-2 in their last 9 meetings. Their last five meetings have gone under the total.

In this Louisiana vs South Alabama Prediction, South Alabama is coming as -4-point home favorites, with the total set at 54 points. Both teams have identical records this season and are both 3-5 against the spread, so I see no value on either side. Both offenses have been struggling, as they score 48.7 points per game combined and all of their last 5 meetings have been low-scoring ones. Take the under 54 points in this one.

Nikos Lagouretos's Free Pick: Under 54

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