The Notre Dame Fighting Irish and Louisville Cardinals meet Saturday in week 6 college football action at Cardinal Stadium. Let’s preview this game and give out a pick and prediction.

Notre Dame Fighting Irish Betting Preview 

The Notre Dame Fighting Irish look for their third road win to improve to 6-1 on the season. Notre Dame has won 4 of its last 5 road games. Sam Hartman is completing 66.2 percent of his passes for 1,458 yards, 14 touchdowns and 0 interceptions. Mitchell Evans and Chris Tyree have combined for 541 receiving yards and 2 touchdowns, while Jayden Thomas has 13 receptions. The Notre Dame Fighting Irish ground game is averaging 192.2 yards per contest, and Audric Estime leads the way with 672 yards and 7 touchdowns. Defensively, Notre Dame is allowing 13 points and 271 yards per game. Howard Cross III leads the Notre Dame Fighting Irish with 35 tackles, Jordan Botelho has 2 sacks and Xavier Watts has 2 interceptions.

Notre Dame Fighting Irish Team Facts

• Notre Dame has won each of its last 13 road games against opponents from the Atlantic Coast Conference.
• Notre Dame has covered the spread in each of its last 10 games as a favorite against AP-ranked teams.
• Notre Dame has won the first half in each of its last 11 games against opponents from the Atlantic Coast Conference.
• Notre Dame has won the first quarter in each of its last four games against opponents from the Atlantic Coast Conference.
• Five of Notre Dame’s last six games against opponents from the Atlantic Coast Conference have gone OVER the total points line.

Louisville Cardinals Betting Preview 

The Louisville Cardinals look for their third home win to remain undefeated on the season. Louisville looks for its first 6-0 start since the 2013 CFB season. Jack Plummer is completing 65.2 percent of his passes for 1,406 yards, 11 touchdowns and 6 interceptions. Jamari Thrash and Ahmari Huggins-Bruce have combined for 635 receiving yards and 7 touchdowns, while Chris Bell has 7 receptions. The Louisville Cardinals ground game is averaging 193.8 yards per contest, and Jawhar Jordan leads the way with 510 yards and 6 touchdowns. Defensively, Louisville is allowing 17.2 points and 327.8 yards per game. TJ Quinn leads the Louisville Cardinals with 32 tackles, Ashton Gillotte has 5 sacks and Cam’Ron Kelly has 2 interceptions.

Louisville Cardinals Team Facts

• The favorite has won each of Louisville’s last 10 games.
• Louisville has covered the spread in each of its last seven games at L&N Federal Credit Union Stadium.
• Louisville has won the first half in each of its last three games against non-conference opponents.
• Louisville has won the first quarter in five of its last six games against non-conference opponents.
• Each of Louisville’s last seven games against non-conference opponents have gone UNDER the total points line.

Matchup/League Facts

• Louisville ranked 7th among FBS teams for Q4 points allowed per game last season (4.2).
• Louisville ranked 8th among FBS teams for H2 points allowed per game last season (7.8).
• Notre Dame ranked 3rd among FBS teams for Q2 points allowed per game last season (3.5).
• Notre Dame ranked T12th among FBS teams for Q2 win percentage last season (.692).

Randy’s Pick

The Notre Dame Fighting Irish are getting the benefit of the doubt because it’s Notre Dame, a popular team for the betting public. However, Notre Dame has been shaky the last two weeks, losing a heartbreaker to Ohio State and escaping Duke, a game it probably should’ve lost. The Louisville Cardinals are a balanced team that’s 11th in total offense and 24th in scoring defense. Louisville just grinded out NC State in a road victory and has allowed 14 or fewer points in 3 of its last 4 games. Night game and the crowd should be out in full force. Give me the Cards and the free points.