Stanford Cardinal (2-3) vs. Notre Dame Fighting Irish (5-0)
October 10, 2026 3:30 pm EDT
The Line: Notre Dame Fighting Irish -38.5 / Stanford Cardinal +38.5; Over/Under: 54.5
(Get latest betting odds)
The Stanford Cardinal and the Notre Dame Fighting Irish meet in week 6 college football action from Notre Dame Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Stanford Cardinal vs. Notre Dame Fighting Irish Prediction.
Stanford Cardinal Recap
The Stanford Cardinal come into this game looking to bounce back from their 57-3 loss at the hands of Wake Forest last time out to sit at 2-3 this season. After this game, Stanford will head home for a game against Elon.
Cardinal Looking To Bounce Back
Davis Warren has thrown for 1,207 yards, 5 touchdowns and an interception on 59.0% passing while Micah Ford leads Stanford in rushing with 302 yards and 4 touchdowns through 5 games this season. Sedrick Irvin sits behind Ford on the ground with 145 yards and 0 touchdowns. Caden High leads the Cardinal in receiving with 266 yards and 17 catches along with 3 touchdowns, while Benji Blackburn trails with 159 yards and 20 catches. On defense, Matt Rose has a team-high 38 tackles while Stanford’s defense as a whole has combined for 4 sacks and 3 interceptions through 5 games this season.
Notre Dame Fighting Irish Recap
The Notre Dame Fighting Irish come into this game looking to add on to their 37-26 win over North Carolina last time out to sit at 5-0 this season. After this game, Notre Dame will head on the road for a game against BYU.
Irish Looking To Stay Unbeaten
CJ Carr has thrown for 1,197 yards, 13 touchdowns and an interception on 71.0% passing while Aneyas Williams leads Notre Dame in rushing with 266 yards and 4 touchdowns through 5 games this season. Nolan James Jr. sits behind Williams on the ground with 262 yards and 3 touchdowns. Jordan Faison leads the Fighting Irish in receiving with 371 yards and 25 catches along with 4 touchdowns, while Micah Gilbert trails with 368 yards and 18 catches. On defense, Drayk Bowen has a team-high 24 tackles while Notre Dame’s defense as a whole has combined for 14 sacks and 5 interceptions through 5 games this season.
Stanford Cardinal @ Notre Dame Fighting Irish Betting Trends: Week 6
Why the Notre Dame Fighting Irish will win
- Notre Dame has won each of its last 24 games against opponents from the Atlantic Coast Conference at Notre Dame Stadium.
- Stanford has lost each of its last 13 road games.
- Notre Dame has covered the spread in each of its last 12 home games against opponents from the Atlantic Coast Conference.
- Stanford has failed to cover the spread in each of its last 10 road games against AP-ranked teams.
- Notre Dame has won the first half in each of its last 18 games against opponents from the Atlantic Coast Conference at Notre Dame Stadium.
- Notre Dame has won the first quarter in each of its last 11 games as a top-10 AP-ranked team against a non-AP-ranked team.
Why the Stanford Cardinal will win
- Stanford has won each of its last four games against top-3 AP-ranked teams.
- Notre Dame has failed to cover the spread in eight of its last nine October games as a top-10 AP-ranked team.
- Stanford has won the first quarter in four of its last five October games against top-10 AP-ranked teams.
- The road team has won the first half in five of the last six games between Stanford and Notre Dame.
Total Points Facts
- Each of Stanford’s last six games against top-15 AP-ranked teams have gone OVER the total points line.
- Six of the last seven games between Stanford and Notre Dame have gone OVER the total points line.
Notre Dame Fighting Irish Player Prop Facts
- Heading into Week 6, CJ Carr ranks T2nd in the league for TD:INT ratio (13.00) this season.
Stanford Cardinal Player Prop Facts
- Heading into Week 6, Chris Davis Jr. ranks 5th amongst FBS players for kick return yards (284) this season.
Matchup/League Facts
- Notre Dame ranks 1st among FBS teams for yards allowed per game this season (216.4).
- Notre Dame has won the first quarter in each of its last nine games – longest active streak in the FBS.
- Stanford has recorded the equal-most home wins by a margin of 10 points or less of any FBS team this season (2).
- Stanford ranks 137th among FBS teams for passing yards allowed per game this season (299.8).
Stanford Cardinal vs. Notre Dame Fighting Irish Prediction
I’m on the Irish here. I get the case to be made for Stanford as this is a huge number to lay. However, Stanford just got drilled in their last game against Wake and we’re starting to see Notre Dame come to play as the Irish team that we expect to see time after time. I think this unfortunately for Stanford is another drill spot so give me the Irish.
