Ole Miss vs Tulane Prediction Football Picks Today 9/20/25
Tulane Green Wave (0-2) vs. Ole Miss Rebels (3-0)
September 20, 2025 3:30 pm EDT
The Line: Ole Miss Rebels -11.5; Over/Under:
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The Tulane Green Wave and the Ole Miss Rebels meet Saturday in college football action from Vaught-Hemingway Stadium. Here’s an Ole Miss vs Tulane prediction. We will look at this from a betting perspective and determine the best Ole Miss vs Tulane pick.
Tulane Green Wave Betting Preview
Tulane kicked off their 2025 campaign with a home matchup against Northwestern on August 30. In that one the Green Wave scored 20 points in the first half but slowed down from there in a 23-3 win. QB Jake Retzlaff was 18-of-31 for 152 yards and a score, while also leading the rush with 10 carries for 113 yards and another TD. Omari Hayes caught nine balls for 74 yards to lead the receivers in the victory.
Game two was a much tighter matchup, this time versus South Alabama. Tulane was up 27-14 by the start of the fourth quarter but ended up just barely eking out a 33-31 win in the end. Retzlaff was 13-of-24 for 125 yards and a TD, but Zuberi Mobley led the rush this time on 11 totes for 82 yards and two scores. Bryce Bohanon caught five balls for 62 yards to top the team’s receivers in the win.
Last weekend versus Duke, the Green Wave jumped out to a 24-9 halftime lead. Tulane held on for the win 34-27, scoring in every quarter along the way. Retzlaff threw for 245 yards this time, and also led the rush with 17 totes for 111 yards and a whopping four scores.
Ole Miss Rebels Betting Preview
Over on the Ole Miss side, they started out their season with a pretty routine matchup versus Georgia State. The Rebels managed to put up points in every quarter (including double-digits in each of the last three) on the way to a 63-7 blowout victory. QB Austin Simmons was 20-of-31 for 341 yards, three scores and two interceptions. Kewan Lacy had a great day on the ground with 16 totes for 108 yards and three scores, while Harrison Wallace caught five balls for 130 yards and a TD of his own.
In game two versus Kentucky, Ole Miss played a much tighter matchup. The Rebels faced an early deficit before scoring 27 points across the second and third quarters. When the dust settled Ole Miss had a road win 30-23. Simmons was 13-of-24 this time with 235 yards and a pair of picks—but did have a rush score. Lacy rushed 28 times for 138 yards and a touchdown, while Harrison Wallace caught four balls for 117 yards to lead the receivers.
Matched up against Arkansas, Ole Miss scored 24 points in the second quarter—while giving up 21 points in that same time frame—on the way to a hard-fought win 41-35. QB Trinidad Chambliss was 21-of-29 for 353 yards and a score while also leading the rush on 15 totes for 62 yards and two touchdowns. Lacy had 17 carries for 44 yards and a TD and Wallace led the receivers with six grabs for 92 yards and a touchdown.
Tulane Green Wave @ Ole Miss Rebels Betting Trends: Week 4
Ole Miss Rebels Player Prop Facts
- Heading into Week 4, Kewan Lacy leads the Southeastern Conference for rush attempts (61) this season.
Tulane Green Wave Player Prop Facts
- Heading into Week 4, Javion White ranks T1st amongst FBS players for interceptions (3) this season.
Matchup/League Facts
- Ole Miss ranks T1st among FBS teams for 4th down conversion percentage this season (100.0).
- Ole Miss ranks T3rd among FBS teams for Q2 points per game this season (19.7).
- Tulane ranks T1st among FBS teams for red zone percentage this season (100.0).
- Tulane ranks T6th among FBS teams for interceptions this season (5).
Ole Miss vs Tulane Prediction
I’ll go with Ole Miss here. The Rebels are coming off a gritty win over a feisty Arkansas team and they’ve got a few things to clean up, though. Ole Miss gave up 526 yards (305 passing), 7.3 yards per play, 29 first downs and a blistering 9-of-12 success rate on third-down conversions in the victory, but the offense was hot enough to counteract it on the other side. The Rebels collected 475 yards (357 passing), 6.8 yards per play, 25 first downs and 8-of-12 on third-down conversions themselves in the shootout. That gives the Rebels 30 or more points in all three games thus far, but it appears they’re also capable of surrendering some big points totals to solid offenses.