South Carolina vs Alabama Prediction Football Picks Today 10/25/25
Alabama Crimson Tide (6-1) vs. South Carolina Gamecocks (3-4)
October 25, 2025 3:30 pm EDT
The Line: South Carolina Gamecocks +11.5 / Alabama Crimson Tide -11.5; Over/Under: 47.5
(Get latest betting odds)
The Alabama Crimson Tide and the South Carolina Gamecocks meet in week 9 college football action from Williams-Brice Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Alabama Crimson Tide vs. South Carolina Gamecocks prediction.
Alabama Crimson Tide Recap
The Alabama Crimson Tide come into this game looking to add on to their 37-20 win over Tennessee last time out to sit at 6-1 this season. After this game, Alabama will have a bye before taking on LSU at home.
Crimson Tide Win 6 In A Row
Ty Simpson has thrown for 1,931 yards, 18 touchdowns and an interception on 70.2% passing while Jam Miller leads the Crimson Tide in rushing with 282 yards and 2 TDs. Germie Bernard has a team-high 33 catches for 472 yards and 5 touchdowns while Ryan Williams has 423 receiving yards with 3 TDs and Isaiah Horton has 272 receiving yards and 5 TDs. Lotzeir Brooks has 255 receiving yards while two more Crimson Tide receivers have 100+ receiving yards as well this season. On defense, Justin Jefferson has a team-high 40 total tackles including 24 solo tackles while Bray Hubbard has a team-high 3 interceptions. Yhonzae Pierre has a team-high 4 sacks and LT Overton has 3 sacks as well this season. As a unit, Alabama’s defense has combined for 13 sacks and 7 interceptions so far this season.
Why the Alabama Crimson Tide will win
- Alabama has won each of its last six games.
- South Carolina has lost eight of its last nine games in October.
- South Carolina has failed to cover the spread in each of its last four home games in October.
- Alabama has covered the spread in five of its last six games.
South Carolina Gamecocks Recap
The South Carolina Gamecocks come into this game looking to rebound from a 26-7 loss at the hands of Oklahoma last time out to sit at 3-4 this season. After this game, South Carolina will head on the road for a game against Ole Miss.
Gamecocks Drop 4 Of Last 5
LaNorris Sellers has thrown for 1,134 yards, 5 touchdowns and 2 interceptions on 64.7% passing while Rahsul Faison has a team-high 281 rushing yards and 3 touchdowns. Vandrevius Jacobs leads South Carolina’s receivers with 21 catches for 343 yards and 2 TDs while Nyck Harbor has 278 receiving yards and 2 TDs. On defense, DQ Smith has a team-high 38 total tackles including 25 solo tackles while Bryan Thomas Jr. has a team-high 4 sacks and Dylan Stewart has 3.5 sacks. As a unit, South Carolina’s defense has combined for 15 sacks and 8 interceptions so far this season.
Why the South Carolina Gamecocks will win
- South Carolina has won each of its last four home games against teams from Alabama.
- South Carolina has covered the spread in eight of its last nine games against teams from Alabama.
Total Points Facts
- Eight of Alabama’s last nine games against conference opponents have gone UNDER the total points line.
- Five of South Carolina’s last six October games as an underdog have gone UNDER the total points line.
Alabama Crimson Tide vs. South Carolina Gamecocks Prediction
I’m on South Carolina and the points here. This is just a tricky spot for Alabama after so many high-profile games in a row and we’ve seen Kalen DeBoer struggle as heavy road chalk over the years. South Carolina will likely treat this as their super bowl as one of the last big home games of the season and I think they could give Alabama a game here. Give me South Carolina and the points.