Colorado Buffaloes (2-3) vs. TCU Horned Frogs (3-1)
October 4, 2025 7:30 pm EDT
The Line: TCU Horned Frogs -14 / Colorado Buffaloes 14; Over/Under: 58.5
(Get latest betting odds)
The Colorado Buffaloes and TCU Horned Frogs meet Saturday in college football action at Amon G. Carter Stadium. Here’s a TCU vs Colorado Prediction. This article will include a TCU vs Colorado Pick.
Colorado Buffaloes Betting Preview
The Colorado Buffaloes lost to BYU, beat Wyoming, and they play Iowa State next. Colorado has won 10 of its last 16 games. Kaidon Salter is completing 67 percent of his passes for 684 yards, 5 touchdowns, and 1 interception. Joseph Williams and Sincere Brown have combined for 431 receiving yards and 4 touchdowns, while Omarion Miller has 11 receptions.
The Colorado Buffaloes ground game is averaging 147.4 yards per contest, and Micah Welch leads the way with 210 yards and 1 touchdown. Defensively, Colorado is allowing 22.8 points and 404.8 yards per game. Tawfiq Byard leads the Colorado Buffaloes with 35 tackles, Arden Walker has 1.5 sacks and RJ Johnson has 1 interception.
TCU Horned Frogs Betting Preview
The TCU Horned Frogs beat SMU, lost to Arizona State, and they play Kansas State next. The TCU Horned Frogs have won 7 of their last 8 games. Josh Hoover is completing 66.7 percent of his passes for 1,242 yards, 11 touchdowns and 4 interceptions. Eric McAlister and Jordan Dwyer have combined for 619 receiving yards and 5 touchdowns, while Joseph Manjack IV has 15 receptions.
The TCU Horned Frogs ground game is averaging 133.5 yards per contest, and Kevorian Barnes leads the way with 156 yards and 1 touchdown. Defensively, TCU is allowing 21.5 points and 389.3 yards per game. Kaleb Elarms-Orr leads the TCU Horned Frogs with 31 tackles, Kylin Jackson has 1.5 sacks and Jamel Johnson has 2 interceptions.
Colorado Buffaloes @ TCU Horned Frogs Betting Trends: Week 6
TCU Horned Frogs Player Prop Facts
- Heading into Week 6, Ed Small ranks T1st amongst qualified players for catch rate (100.0%) this season.
Colorado Buffaloes Player Prop Facts
- Heading into Week 6, Quentin Gibson ranks 6th amongst FBS players for kick return yards (282) this season.
Matchup/League Facts
- TCU ranks 7th among FBS teams for Q3 points per game this season (10.5).
- TCU ranks T9th among FBS teams for 4th down conversion percentage this season (83.3).
- Colorado ranks 129th among FBS teams for 1st downs against this season (114).
- Colorado ranks 124th among FBS teams for rushing yards allowed per game this season (197.2).
TCU vs Colorado Prediction
TCU is the better team with the more balanced attack, but this line feels a bit rich. TCU has played a lot of games close to the vest this season, and it’s led to failed covers in 2 of its last 3 games. Colorado has a bend but don’t break defense, and I’d assume the offense is going to come along eventually. There’s talent on this Colorado roster, and nearly upsetting BYU should provide confidence.
Colorado has covered each of its last 5 games as a double-digit underdog. TCU has failed to cover 6 of its last 9 games as a double-digit favorite. I’ll grab the points with the Buffs on the road.
