College Football

Virginia vs Louisville Prediction 10-12-24 College Football Picks

Louisville Cardinals (3-2) vs. Virginia Cavaliers (4-1)
October 12, 2024 3:30 pm EDT
The Line: Virginia Cavaliers +7.5 / Louisville Cardinals -7.5; Over/Under: +54.5
(Get latest betting odds)

The Louisville Cardinals and the Virginia Cavaliers meet in week 6 college football action from Scott Stadium on Saturday afternoon. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Louisville vs. Virginia prediction.

Louisville Recap

The Louisville Cardinals come into this one looking to rebound from back-to-back losses after a 34-27 loss to SMU last time out to fall to 3-2 on the year. After this game, Louisville will head back home for an important matchup against Miami.


Cardinals Trying To Right The Ship

Tyler Shough has thrown for 1,443 yards, 13 touchdowns, and 2 interceptions on 64.5% passing while Isaac Brown has rushed for a team-high 362 yards. Duke Watson, Donald Chaney, and Keyjuan Brown each have 100+ rushing yards as well while Ja’Corey Brooks has a team-high 25 receptions for 489 yards and 6 TDs. Chris Bell has 11 grabs for 195 yards and another three Cardinals have 100+ receiving yards as well on the year. On defense, Stanquan Clark leads Louisville with 31 total tackles while Tramel Logan has 3 sacks to lead Louisville, and Tamarion McDonald and Jared Dawson each have 2 sacks.

Why the Louisville Cardinals will win

  • Virginia has lost eight of its last 10 home games against conference opponents.
  • Louisville has won 16 of its last 21 games against non-AP-ranked teams.
  • The favorite has covered the spread in four of Louisville’s last five games.

Virginia Recap

The Virginia Cavaliers come into this one looking to build on back-to-back wins after a 24-14 win over Boston College last time out, improving to 4-1 on the year. After this game, Virginia will head on the road for a game with Clemson.

Cavaliers Looking To Make Noise In ACC

Anthony Colandrea has thrown for 1,211 yards, 8 touchdowns, and 4 interceptions on 66.4% passing while also rushing for 158 yards and 2 scores. Xavier Brown has a team-high 315 rushing yards while Kobe Pace has 293 rushing yards and 2 scores. Malachi Fields leads the Cavaliers in receiving with 28 grabs for 412 yards and 3 TDs while Trell Harris has 201 receiving yards and Tyler Neville has 197 receiving yards as well this season. On defense, Antonio Clary has a team-high 48 total tackles while Virginia has combined as a unit for 10 sacks and 3 interceptions so far this season.

Why the Virginia Cavaliers will win

  • Louisville has lost each of its last five October games as a road favorite.
  • Virginia has won three of its last four October games as a home underdog.
  • Louisville has failed to cover the spread in each of its last eight October games as a road favorite.
  • Virginia has covered the spread in each of its last six games in October.

Virginia vs Louisville Prediction

I’m leaning towards Louisville here. I think the Cardinals are just the better team that has caught a couple of bad breaks in the last couple of weeks. Virginia is a solid team but I feel like I need to see the Cavaliers beat the challenge of adversity beating a banged-up Boston College team and taking out Coastal Carolina on the road is nice, but Louisville has a top passing offense which is the weakness of this Virginia defense, and the Cardinals are the better defensive unit across the board. Give me Louisville.

Chris Ruffolo's Free Pick: Louisville -7.5

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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