Draftkings NFL Showdown Picks: Falcons vs. 49ers 10/19/25
Atlanta Falcons vs. San Francisco 49ers
October 19, 2025 8:20 pm EDT
This Sunday night, the NFL presents Draftkings football fans with a regular season matchup featuring the Atlanta Falcons and the San Francisco 49ers. Let’s take a look at this game from a DFS perspective.
Before we dive into the Atlanta Falcons vs. San Francisco 49ers game let’s review the rules for the Draftkings single game showdown contest.
Draftkings Single Game Showdown Contest Rules
You have $50,000 to utilize on five players from either team. However, one of those players will be designated as your team captain. The captain accumulates 1.5 times the standard fantasy points. Additionally, the captain is 1.5 times the standard cost of the flex position.
The remaining four players in your lineup will receive the standard fantasy points. Having stated that, it is highly important for you to identify the correct player for your captain position if you hope to win a large field DFS GPP (guaranteed prize pool) showdown contest.
If you have additional questions regarding the rules for the single game showdown contest, I recommend that you check out the Draftkings website for more details.
*I recommend that all readers review the starting lineups for both teams prior to setting your DFS lineup for this one game slate.
Here are my Draftkings picks for this week’s Falcons vs. 49ers matchup.
Draftkings NFL Showdown Picks
Captain-Christian McCaffrey, Running Back, San Francisco 49ers $12,000
Veteran running back Christian McCaffrey has certainly been a standout performer for the San Francisco 49ers in 2025. With that said, how has McCaffrey performed from a data perspective this season? Let’s review McCaffrey’s relevant key player game data from the 2025 NFL regular season to better shed light on the talented running back’s overall contributions to his team.
In the six games that running back Christian McCaffrey has played for the San Francisco 49ers in the 2025 NFL regular season, McCaffrey has amassed 336 rushing yards, one rushing touchdown, 46 receptions, 444 receiving yards and three receiving touchdowns.
Looking at the data just presented more closely, in the six games that McCaffrey has played this season, McCaffrey has averaged a rather impressive 24.1 Draftkings points.
More recently, in the San Francisco 49ers 16-15 win over the Arizona Cardinals last month, San Francisco running back Christian McCaffrey played exceptionally well. Let me be more specific. In the San Francisco 49ers defeat of the Cardinals, McCaffrey tallied 52 rushing yards, ten receptions and 88 receiving yards.
In my view, Christian McCaffrey is the most likely player to post the most Draftkings points in this NFL regular season game. For that specific reason, I am rolling with San Francisco 49ers running back Christian McCaffrey at the captain position for this one game NFL DFS slate.
Flex Plays
Bijan Robinson, Running Back, Atlanta Falcons $12,200
Running back Bijan Robinson has played exceptional football for the Atlanta Falcons this season. In the five games that Robinson has played for the Atlanta Falcons in the 2025 NFL regular season, Robinson has compiled a massive 484 rushing yards, two rushing touchdowns, 24 receptions, 338 receiving yards and one receiving touchdown.
In conclusion, I fully expect Atlanta Falcons running back Bijan Robinson to continue his outstanding play in Sunday night’s NFL regular season matchup with the San Francisco 49ers.
Flex plays I like to play well in this Sunday night’s NFL regular season contest (Draftkings price noted): Drake London, Wide Receiver (Atlanta Falcons) $10,200: Kendrick Bourne, Wide Receiver (San Francisco 49ers) $8,200: Tyler Allgeier, Running Back (Atlanta Falcons) $5,200: Kyle Pitts Sr., Tight End (Atlanta Falcons) $5,800: Eddy Pineiro, Kicker (San Francisco 49ers) $5,400.
