FanDuel Best MLB DFS Picks: Mariners vs. Astros 9/19/25
Seattle Mariners vs. Houston Astros
September 19, 2025 8:10 pm EDT
Major League Baseball presents FanDuel baseball fans with an American League matchup featuring the Seattle Mariners and the Houston Astros. Let’s take a look at this MLB game from a DFS perspective.
Before we dive into the Seattle Mariners vs. Houston Astros game let’s review the rules for the FanDuel single game showdown contest.
FanDuel Single Game Contest Rules
Here are the FanDuel single game contest rules. You have $60,000 to utilize on five players from either team. However, one of those players will be designated as your team MVP. The MVP accumulates 1.5x times the standard FanDuel fantasy points value. Additionally, the MVP is 1.5 times the standard cost of the flex position.
The remaining five players in your lineup will be flex plays. The five flex positions will receive the standard FanDuel points value. Having stated that, it is highly important for you to identify the correct player for your MVP position if you hope to win a large field GPP (guaranteed prize pool) FanDuel single game contest.
If you have additional questions regarding the rules for the single game contest, I highly recommend that you check out the FanDuel website for more details.
*It should be noted that FanDuel does not utilize the pitcher position in single game MLB contests. Having stated that, only batters are available for single game MLB lineups on the FanDuel platform.
Here are my FanDuel picks for this evening’s Mariners vs. Astros matchup.
FanDuel MLB DFS Picks
MVP-Julio Rodriquez, Outfielder, Seattle Mariners $13,200
On Friday night, Major League Baseball presents the opening game of a three-game American League series featuring the Seattle Mariners and the Houston Astros.
How are these two teams playing entering today’s MLB game? The Seattle Mariners arrive at the first game of this three-game series with the Houston Astros playing good baseball. More specifically, the Mariners have won 11 of the team’s last 12 games played in the 2025 MLB regular season, including a dominant 11-2 victory over the Los Angeles Angels five days ago.
Similar to the Seattle Mariners, the Houston Astros are currently playing quality baseball entering this evening’s game. The Astros have won five of the team’s last six games played in the 2025 MLB regular season, including an 11-3 win over the Atlanta Braves last week.
Now that we have identified how both of these teams are currently playing let’s turn our attention to today’s contest. Outfielder Julio Rodriguez has certainly been a standout performer for the Seattle Mariners this season. Having stated that, how has the veteran outfielder performed from a statistical perspective? Let’s examine Rodriguez’s relevant game data from the 2025 MLB regular season to answer that question.
In the 152 games that Seattle Mariners outfielder Julio Rodriguez has played in the 2025 MLB regular season, Rodriguez has compiled a .269 batting average, 30 home runs (16th in MLB), 38 walks, 93 RBIs (runs batted in), 27 stolen bases (19th in MLB), 93 runs scored and a .796 OPS (On-Base Plus Slugging)
What did we learn from the data just presented? Clearly, Julio Rodriguez can post a high number of DFS points on any given night. With that said, I fully expect that trend to continue in tonight’s matchup with the Houston Astros.
In conclusion, I think that Seattle Mariners outfielder Julio Rodriguez is the most likely player to compile the most FanDuel points in this MLB game. For that specific reason, I am backing Julio Rodriguez at the MVP position for this one game MLB DFS slate.
Flex plays I like to play well in this MLB regular season game (FanDuel price noted): Randy Arozarena, Outfielder (Seattle Mariners) $13,200: Jeremy Pena, Shortstop (Houston Astros) $10,800: Jose Altuve, Second Baseman (Houston Astros) $8,000.
