A's vs. Diamondbacks Pick – MLB Predictions & Odds 5/16/23

Chris RuffoloMay 16, 2023
A's vs. Diamondbacks Pick – MLB Predictions & Odds 5/16/23 player photo
Credit: USA Today Sports

The Arizona Diamondbacks and the Oakland A’s meet in an interleague matchup in MLB action from the Oakland Coliseum on Tuesday. Let’s dive into the odds, starting pitching matchup, history and make a prediction for this game.


Arizona is listed as a -145 road favorite while Oakland is a +125 home underdog. The total for this game is set at 9 runs.

Starting Pitching Matchup

Tommy Henry will start for Arizona here and is 1-1 with a 4.43 ERA and 9 strikeouts this season. Oakland will start Kyle Muller here and is 1-3 with a 7.34 ERA and 27 strikeouts this season.

Matchup History

Arizona’s 5-2 win on Monday snapped Oakland’s six-game head-to-head win streak in this matchup.


Arizona is 7-3 in their last 10 road games and 8-3 in their last 11 interleague games while the over is 20-8 in their last 28 interleague road games. Oakland is 29-68 in their last 97 home games and 13-38 in their last 51 games against a team with a winning record while the over is 12-4 in their last 16 games following a loss.


I’m backing the Diamondbacks here. I’m not the biggest Tommy Henry fan, but this does feel like a reasonable spot for Henry to have a good start against an Oakland team that’s been absolutely atrocious for much of the season so far. The A’s just aren’t imposing offensively and I think Henry does well enough to get the D-Backs the win here.

Chris Ruffolo's Free Pick:Arizona -145
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Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg