Angels vs Guardians Prediction 4/6/25 MLB Picks Today

The Cleveland Guardians and Los Angeles Angels meet Sunday in MLB action at Angel Stadium. Here’s a Angels vs Guardians Prediction. This article will include a Angels vs Guardians Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 3-5 on the year and play the White Sox, Royals, and Orioles next. The Cleveland Guardians are batting .234 on the season, have a .309 OBP, and a .421 slugging percentage. The Cleveland Guardians pitching staff has a 5.16 ERA and a 1.57 WHIP. Steven Kwan leads the Cleveland Guardians with 11 hits and 3 RBI, while Carlos Santana and Jose Ramirez have combined for 17 hits and 9 RBI.

Luis Ortiz gets the ball for the Cleveland Guardians, and he is 0-1 with a 13.50 ERA and 2 strikeouts this season. This will be Ortiz’s second career game against the Los Angeles Angels.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 5-3 on the year and play the Rays, Astros, and Rangers next. The Los Angeles Angels are batting .228 on the season, have a .303 OBP, and a .390 slugging percentage. The Los Angeles Angels pitching staff has a 4.81 ERA and a 1.41 WHIP. Nolan Schanuel leads the Los Angeles Angels with 9 hits and 4 RBI, while Logan O’Hoppe and Taylor Ward have combined for 15 hits and 10 RBI.

Tyler Anderson gets the ball for the Los Angeles Angels, and he is 0-0 with a 5.40 ERA and 4 strikeouts this season. Anderson is 1-0 with a 3.21 ERA and 5 strikeouts in his career against the Cleveland Guardians.

Why the Los Angeles Angels will win

• The Angels have won seven of their last eight games as underdogs against AL Central opponents following a home win.
• The Guardians have lost seven of their last eight games at Angel Stadium of Anaheim against AL West opponents that held a winning record.
• The Guardians have failed to cover the run line in nine of their last 10 games after playing the previous day.
• The Angels have covered the run line in seven of their last eight games as underdogs against AL Central opponents following a home win.
• The Guardians have trailed after 3 innings in four of their last five games at Angel Stadium of Anaheim against American League opponents that held a winning record.
• The Guardians have trailed after 5 innings in six of their last seven road games against opponents that held a winning record.

Why the Cleveland Guardians will win

• The Guardians have won each of their last six day games against AL West opponents.
• The Angels have lost seven of their last eight games against teams that held a losing record.
• The Angels have failed to cover the run line in each of their last seven games against American League opponents following a win.
• The Guardians have covered the run line in each of their last four road games against AL West opponents following a road loss.
• The Angels have trailed after 5 innings in each of their last six day games against American League opponents that held a losing record.
• The Angels have trailed after 3 innings in 10 of their last 13 day games against American League opponents that held a losing record.

Angels vs Guardians Prediction

The Guardians are the better team on paper, so they’re going to get the benefit of the doubt. The problem is the Guardians aren’t playing like it, as their offense hasn’t been consistent, and the pitching staff has been getting rocked, in this series especially. I’ve bashed the Angels a lot over the years, but they’re playing decent ball lately, and they’ve produced five or more runs in five straight games. We’re also getting a two-time all star pitcher at home with the plus money. You can do a lot worse than taking a chance on the Angels on Sunday afternoon.