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Diamondbacks vs Reds Prediction 8/24/25 MLB Picks Today

Cincinnati Reds (67-63) vs. Arizona Diamondbacks (64-66)
August 24, 2025 4:10 pm EDT
The Line: Arizona Diamondbacks -136 / Cincinnati Reds 112; Over/Under: 9
(Get latest betting odds)

The Cincinnati Reds and the Arizona Diamondbacks meet Sunday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Diamondbacks vs Reds Prediction.

Starting Pitching Matchup

The Cincinnati Reds will send out Brady Singer here and Singer is 11-9 with a 4.18 ERA and 123 strikeouts this season. In his career, Singer is 2-0 with a 2.00 ERA and 14 strikeouts against the Diamondbacks. Zac Gallen will get the start for the Diamondbacks here and is 9-13 with a 5.28 ERA and 134 strikeouts this season. In his last five starts against the Reds, Gallen is 1-2 with a 3.48 ERA and 27 strikeouts.

Cincinnati Reds Recap

The Cincinnati Reds come into this game looking to bounce back after ending up on the wrong side of a 10-1 loss at the hands of the Arizona Diamondbacks last time out to fall to 67-63 this season. After this series, the Reds will head on the road for a series against the Los Angeles Dodgers.

Reds Lose Three In A Row

Elly De La Cruz has 135 hits with 19 home runs, 76 RBIs, 25 doubles and 31 stolen bases while TJ Friedl has 121 hits with 18 doubles, 10 home runs and 40 RBIs with 11 stolen bases. Gavin Lux has added 100 hits with 21 doubles and 48 RBIs while Spencer Steer has 15 home runs and 59 RBIs and Matt McLain has added 11 homers, 40 RBIs and 16 stolen bases as well on the year. Jose Trevino’s also chipped in 19 doubles as well this season.

Why the Cincinnati Reds will win

  • The Reds have won each of their last six day games against NL West opponents that held a losing record.
  • The Diamondbacks have lost three of their last four games as favorites against National League opponents.
  • The underdogs have covered the run line in each of the last 10 games between the Reds and Diamondbacks.
  • The Diamondbacks have failed to cover the run line in each of their last seven games as favorites.

Cincinnati Reds Player Prop Facts

  • Ke’Bryan Hayes has recorded at least one Double in each of the Reds’ last three games as underdogs.
  • Elly De La Cruz has recorded two hits in each of the Reds’ last six road games against NL West opponents.
  • Brady Singer has recorded six or more strikeouts in four of his last five appearances against NL West opponents that held a losing record.
  • Brady Singer has recorded a win in four of his last five appearances.
  • Santiago Espinal has hit a home run in three of his last five appearances in day games against NL West teams that held a losing record.
  • Elly De La Cruz ranks T8th in the league in Steals (31) this season.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to add on to their win over the Reds from Sunday to improve to 64-66 on the year. After this series, the Diamondbacks will head on the road for a series against the Milwaukee Brewers.

Diamondbacks Pick Up 4th Straight Win

Corbin Carroll has 113 hits with 27 home runs, 65 RBIs, 16 triples and 22 doubles this season. Carroll also has 17 stolen bases and Geraldo Perdomo has a team-high 22 stolen bases as well as 13 home runs and 81 RBIs with a team-high 134 hits this season. Ketel Marte’s added 23 home runs and 56 RBIs as well on the year and Lourdes Gurriel has 115 hits with 23 doubles, 17 home runs and 71 RBIs.

Why the Arizona Diamondbacks will win

  • The Diamondbacks have won each of their last seven home games against NL Central opponents that held a winning record.
  • The Reds have lost five of their last six games at Chase Field.
  • The Diamondbacks have covered the run line each of their last five day games against NL Central opponents that held a winning record.
  • The Reds have failed to cover the run line in five of their last six road games against National League opponents after playing the previous day.

Arizona Diamondbacks Player Prop Facts

  • Lourdes Gurriel Jr. has hit a home run in each of the Diamondbacks’ last two day games.
  • Corbin Carroll has recorded a Double in each of the Diamondbacks’ last three home games against NL opponents.
  • Zac Gallen has recorded five or more strikeouts in each of his last eight appearances in day games against NL teams that held a winning record.
  • Lourdes Gurriel Jr. has recorded at least one hit in each of the Diamondbacks’ last 13 games as favorites.
  • Zac Gallen has recorded a win in four of his last five appearances against NL opponents.
  • Corbin Carroll ranks 5th amongst qualified players for Slugging Percentage (.556) this season.

Total Runs Facts

  • Twelve of the Reds’ last 13 day games after playing the previous day have gone UNDER the total runs line.
  • Each of the Diamondbacks’ last four home games against National League opponents have gone OVER the total runs line.

Diamondbacks vs Reds Prediction

I’m on the over in this one. I don’t trust either starter in this matchup, as Brady Singer’s been hit hard more often than not on the road this season. Zac Gallen still has not been able to put it together for sustained periods of time, and he’s been prone to giving up runs as well. I also am not a fan of either bullpen in this game either, so give me the over here.

Chris Ruffolo's Free Pick: Over 9

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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