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Arizona Diamondbacks vs San Francisco Giants Prediction 9-25-24 MLB Picks

San Francisco Giants (78-79) vs. Arizona Diamondbacks (87-70)
September 25, 2024 9:40 pm EDT
The Line: Arizona Diamondbacks -222 / San Francisco Giants +184; Over/Under: +8.5
(Get latest betting odds)

In this article, we will formulate an Arizona Diamondbacks vs San Francisco Giants  Prediction for this MLB game on Wednesday, September 25th, at Chase Field.

Giants Dominated

The Giants faced off against Diamondbacks on Tuesday and they scored 11 runs on the way to the victory. Brett Wisley hit a home run and drove in three RBIs. The Giants are averaging 4.27 runs while their pitching is giving up 4.31 runs per game.


The offense is ranked 17th in the league while the pitching is ranked 15th. Matt Chapman has hit 26 home runs and driven in 75 RBIs so far this season. Getting the start for the Giants will be Mason Black who sits with a 1-5  record and an ERA of 5.44. In his last start against the Kansas City Royals, he went 5.2 innings giving up four this and zero runs. 

Diamondbacks Bats Need to be Better

The Diamondbacks failed to score any runs on Tuesday and that was the difference. The Diamondbacks are going to need to get the offense out to a fast start. The Diamondbacks are averaging 5.52 runs per game while their defense is giving up 4.85 runs per game.

The offense is ranked 1st while the defense is ranked 26th in the league. They have a run differential of 0.68 runs per game which is 5th in the league. Ketel Marte has hit 35 home runs and has driven 93 RBIs so far this season. Getting the start for the Diamondbacks will be Zac Gallen, who sits with a 13-6 record and an ERA of 3.74. In his last start against the Milwaukee Brewers, he went five innings giving up seven hits and four runs. 

Arizona Diamondbacks vs San Francisco Giants Prediction

Black is coming off a strong start but overall he has struggled and he’s going to really struggle again here. Gallen gave up seven hits and four runs in his last start but overall he has been better sitting with an EAR of 3.74. The Giants bats are going to be ice cold and their lack of scoring will be the difference as the Diamondbacks are going to get the job done. Back the Diamondbacks on the money line to cash.

Shane Mickle's Free Pick: Diamondbacks -1.5

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Shane Mickle

Sports is about all Shane knows in this life! He has a passion for sports and writing, which makes working for Sportschatplace a perfect job for him! If you find him cheering for a team it's usually a Minnesota team, or the Kansas Jayhawks!

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