Astros vs Giants Prediction 4/1/25 MLB Picks Today

In this article, we will formulate an Astros vs Giants prediction for this MLB game on Tuesday, April 1st, at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup. 

Houston Astros Betting Preview

The Houston Astros are 2-2 this year after they lost game one by a score of 7-2 on Monday night. Houston allowed the first five runs in the game, but they did score two runs in the eighth to avoid being shut out. The Astros recorded just three hits in the game, and they were led by Paredes, who went 1-3 with two RBIs and one walk. Houston started Ronel Blanco, who allowed three earned runs and three hits over 5.0 innings, while Contreras allowed two earned runs and two hits in the sixth. 

Prior to that loss, the Astros won two out of three against the Mets by scores of 3-1, 1-3, and 2-1. The Houston pitching staff has a 2.75 ERA with a 1.08 WHIP and a .171 opponent batting average, while the offense has scored eight runs with a .157 batting average and a .269 opponent batting average this year. Yordan Alvarez and Isaac Paredes have led Houston with two RBIs each, but Alvarez is hitting just .083 so far this year. The projected starting pitcher for Houston is Hayden Wesneski, who was 3-6 with a 3.86 ERA and a 1.14 WHIP over 67.2 innings pitched with the Cubs in 2024. 

San Francisco Giants Betting Preview

The San Francisco Giants are 3-1 this season after they captured a 7-2 win on Monday night. San Francisco scored one run in the second inning, one in the fifth, and three in the sixth, before adding two insurance runs in the ninth. The Giants recorded nine hits in the game, and they were led by Flores, who went 2-4 with one home run and four RBIs in the win. San Francisco started Hicks, who went 6.0 innings and allowed just one hit for the win, while Bivens allowed two earned runs and two hits over 0.2 innings in relief. 

Prior to that game, the Giants won two out of three against the Reds by scores of 6-4, 2-3, and 6-3. The San Francisco pitching staff has a 3.09 ERA with a 0.97 WHIP and a .192 opponent batting average, while their offense has scored 21 runs with a .226 batting average and a .276 on-base percentage this year. Wilmer Flores has led San Francisco with three home runs and eight RBIs, while Heliot Ramos has added two home runs and four RBIs this season. The projected starting pitcher for San Francisco is Logan Webb, who is 0-0 with a 5.40 ERA and a 1.80 WHIP over 5.0 innings pitched this season. Webb allowed three earned runs and six hits over 5.0 innings against the Reds in his first start. 

Why the Giants will beat the Astros

• The Giants have won eight of their last nine night games against American League opponents.
• The Astros have lost each of their last four home games against teams that held a winning record.
• The Astros have failed to cover the run line each of their last seven home games against teams that held a winning record.
• The Giants have covered the run line in each of their last seven night games against American League opponents.
• The Giants have won the first inning in four of their last five night games against American League opponents.
• The Giants have led after 3 innings in each of their last four games against American League opponents.
• The Giants have led after 5 innings in each of their last seven night games against American League opponents.

Total Runs Facts

• Each of the Astros’ last six night games as underdogs have gone UNDER the total runs line.
• Each of the Giants’ last four games as favorites against AL West opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last 13 home games against National League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Giants’ last eight night games against AL West opponents.

Astros vs Giants Prediction 

San Francisco comes into this matchup with a 3-1 record to start the season, and they have scored at least six runs in three of their four games. The Giants have done a very good job of driving in runs, and that should continue against Wesneski in this game. Houston is just 2-2 through their first four games, and their offense has been brutal. The Astros have scored a total of eight runs in four games, which should allow Webb to bounce back from a rocky first start. Take the Giants here.