Philadelphia Phillies (47-32) vs. Houston Astros (46-33)
June 25, 2025 8:10 pm EDT
The Line: Houston Astros 129 / Philadelphia Phillies -157; Over/Under: 7.5
(Get latest betting odds)
In this article, we will formulate an Astros vs Phillies prediction for this MLB game on Wednesday, June 25, at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup.
Philadelphia Phillies Betting Preview
The Philadelphia Phillies (47-32, 21-18 Away) won nine of the last 12 games and four consecutive series after defeating the Chicago Cubs, sweeping the Toronto Blue Jays, and beating the Miami Marlins and New York Mets. In Game 1 of the current series in Houston, however, Philadelphia failed to score a run in a 1-0 loss, the first time the Phillies haven’t scored since May 10. Ranger Suarez took the loss after allowing one run on four hits with seven strikeouts and two walks in 7.2 innings.
This year, the Phillies average 4.73 runs per game (7th in the MLB) on a .258/.332/.407 triple-slash. When it comes to pitching, the Phillies’ staff has a 3.89 ERA (15th) and 1.27 WHIP (16th). Kyle Schwarber leads the Phillies with a .247 batting average, 24 home runs, and 55 RBI this season.
The projected starting pitcher for the Phillies is Zack Wheeler, who is 7-2 in 15 starts this season, with a 2.61 ERA and 0.91 WHIP in 93.0 innings.
Houston Astros Betting Preview
The Houston Astros (46-33, 30-13 Home) are unbeaten in the previous nine series, including the wins over the Seattle Mariners, Minnesota Twins (sweep), and most recently, the Los Angeles Angels. Houston opened a three-game series against Philadelphia with a narrow, 1-0 victory on Tuesday. Cooper Hummel broke the deadlock with a solo homer in the 8th inning, while Framber Valdez pitched for 7.0 innings in a no-decision, allowing no runs on four hits with three strikeouts and four walks. Bryan Abreu was credited with the win.
This season, the Astros average 4.27 runs per game (17th in the MLB) on a .257/.323/.402 triple-slash. When it comes to pitching, the Astros’ staff has a 3.52 ERA (7th) and 1.16 WHIP (2nd). Isaac Paredes leads the Astros with a .254 batting average, 16 home runs, and 45 RBI this season.
Colton Gordon will take the mound for the Astros on Wednesday. The 26-year-old left-hander has a 2-1 record in seven starts this year with a 4.54 ERA and 1.37 WHIP in 35.2 innings.
Why the Phillies will beat the Astros
- The Phillies have won each of their last four games following a loss.
- The Astros have lost five of their last six home games against National League opponents following a home win.
- The Phillies have covered the run line in nine of their last 10 games as road favorites against American League opponents following a loss.
- The Astros have failed to cover the run line each of their last seven Wednesday night games against teams that held a winning record.
- The Phillies have led after 3 innings in six of their last eight games as road favorites against AL West opponents.
- The Astros have trailed after 5 innings in 15 of their last 20 games as home underdogs against NL East opponents.
Total Runs Facts
- Ten of the last 11 games between the Phillies and Astros have gone UNDER the total runs line.
- Five of the Phillies’ last six games as favorites against AL West opponents have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last five games against National League opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Phillies’ last four games as road favorites against AL West opponents.
Matchup/League Facts
- The Astros rank 1st in the league for hits allowed this season (566).
- The Astros rank 2nd in the league for runs allowed this season (287).
- The Phillies are one of only three teams in the league to rank top 10 in both strikeouts and walks allowed this season.
- The Phillies rank 4th in the league for on-base percentage this season (.331).
Astros vs Phillies Prediction
The Astros won six of the previous ten H2H encounters, including the last two in which Philadelphia failed to score. I am going with the Phillies in this one, though, because of Zack Wheeler, who has been excellent this year. Wheeler bounced back from his poor start against Atlanta and surrendered just two runs in his last three starts, two of which were against the Cubs and Mets. Colton Gordon, on the other hand, allowed multiple runs in all but one start this season, and I am sure the Phillies will score multiple runs off of him following last night’s dud. Back the Phillies
