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Astros vs Twins Prediction 6/15/25 MLB Picks Today

Minnesota Twins (36-34) vs. Houston Astros (40-30)
June 15, 2025 2:10 pm EDT
The Line: Houston Astros -137 / Minnesota Twins +112; Over/Under: 8.5
(Get latest betting odds)

The Minnesota Twins and the Houston Astros meet Sunday in MLB action from Daikin Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Astros vs Twins Prediction.

Starting Pitching Matchup

The Minnesota Twins will send out Simeon Woods-Richardson for the start here, and Woods-Richardson is 2-3 with a 5.74 ERA and 39 strikeouts this season. In his career, Woods-Richardson is 0-0 with a 4.35 ERA and 10 strikeouts against Houston. Brandon Walter will get the start for the Astros here and is 0-0 with a 1.64 ERA and 10 strikeouts this season. This will be Walter’s first career start against the Twins.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to bounce back from their 3-2 loss at the hands of the Astros in Saturday’s matchup to drop to 36-34 on the year. After this series, the Twins will head on the road for a series against the Cincinnati Reds.

Twins Lose 7 Of Their Last 9

Byron Buxton has 56 hits along with 8 doubles, a team-high 11 home runs, and 41 RBIs with 12 stolen bases and 3 triples, while Carlos Correa has 53 hits with 13 doubles, and Willi Castro has 48 hits with 10 doubles as well. Harrison Bader added 6 home runs and 24 RBIs while Buxton contributed a team-high 66 strikeouts as well this season. Ty France has also added 68 hits, 11 doubles, 5 home runs, and 37 RBIs, and Trevor Larnach chipped in 63 hits with 9 doubles, 10 home runs, and 32 RBIs as well this season.

Why the Minnesota Twins will win

  • The Twins have won 11 of their last 12 games as underdogs against AL West opponents following a loss.
  • The Astros have lost five of their last six games as favorites against the Twins following a win.
  • The Twins have covered the run line in each of their last 12 games as underdogs against AL West opponents following a loss.
  • The Astros have failed to cover the run line in each of their last four games as home favorites against AL Central opponents following a win.

Minnesota Twins Player Prop Facts

  • Carlos Correa has recorded at least one Double in three of his last four appearances with the Twins as road underdogs against the Astros.
  • Ty France has recorded at least one hit in each of his last nine appearances with his team as an underdog against AL West opponents.
  • Byron Buxton has scored at least one run in each of his last five appearances with the Twins as road underdogs.
  • Trevor Larnach has hit a home run in each of his last two appearances with the Twins as underdogs against the Astros.
  • Byron Buxton has recorded an RBI in each of his last eight Sunday appearances.

Houston Astros Recap

The Houston Astros come into this game looking to add on to their win over the Twins from Saturday’s matchup to improve to 40-30 on the year. After this series, the Astros will head on the road for a series against the Athletics.

Astros Win Four In A Row & 7 of Last 9

Jose Altuve has 72 hits, including 10 doubles, 10 home runs, and 30 RBIs. Jeremy Pena also has 89 hits with 15 doubles, 9 homers, and 34 RBIs with 14 stolen bases, while Yordan Alvarez has 4 doubles and 18 RBIs with 21 strikeouts as well. Jake Meyers has 12 doubles as well, and Christian Walker has 9 home runs and 33 RBIs, but has also accrued a team-high 79 strikeouts so far this season. Altuve also has 6 stolen bases, while Jake Meyers has 11 stolen bases this season. Isaac Paredes also has a team-high 15 home runs with 42 RBIs of his own, and Cam Smith has contributed 3 homers and 23 RBIs.

Why the Houston Astros will win

  • The Twins have lost eight of their last nine day games against American League opponents.
  • The Astros have won seven of their last eight games after playing the previous day.
  • The Twins have failed to cover the run line in 10 of their last 12 day games against American League opponents.
  • The Astros have covered the run line in five of their last six games against the Twins.

Houston Astros Player Prop Facts

  • Jose Altuve has recorded at least one Double in three of the Astros’ last four games against AL Central opponents at Daikin Park.
  • Jeremy Pena has recorded two or more hits in each of the Astros’ last seven games as home favorites against AL Central opponents.
  • Jeremy Pena has scored at least one run in each of the Astros’ last seven home games.
  • Isaac Paredes has hit a home run in each of his last two appearances at Daikin Park against AL Central opponents that held a winning record.
  • Isaac Paredes has recorded at least one RBI in each of his last five home appearances against AL Central opponents.
  • Jeremy Pena ranks 3rd in the league in Hits (89) this season.

Total Runs Facts

  • Four of the Twins’ last five day games after playing the previous day have gone OVER the total runs line.
  • Four of the last five games between the Twins and Astros at Daikin Park have gone UNDER the total runs line.

Astros vs Twins Prediction

I’m on the Astros here. I get the case to be made for the Twins in spots, but the Twins can be a team that runs very hot and cold. When the run is cold, it’s like dealing with a block of ice, as Minnesota gets frigid real quick. Woods-Richardson didn’t look good in his return to the lineup for Minnesota, and I don’t think it gets any better here. Give me the Astros.

Chris Ruffolo's Free Pick: Houston Astros -137

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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