Astros vs White Sox Prediction 7/24/26 MLB Picks Today

In this article, we will formulate a Astros vs White Sox Prediction for this MLB matchup on Friday, July 24^th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Preview

The Chicago White Sox have a 54-47 record this season and are sitting in the 1st place of the AL Central. They have a 31-17 home record and are coming off a 4-2 road win against the Rangers. They will face the Yankees and the Rays next.

The Chicago White Sox have a .240 batting average this season, .318 OBP and .409 Slugging percentage. Chicago’s pitching staff has a 4.08 ERA and 1.31 WHIP. Sam Antonacci is the team’s best hitter with a .278 batting average. Miguel Vargas leads the team in RBI with 61, while Colson Montgomery adds a team-high 24 home runs.

Davis Martin (R) is the projected starting pitcher for the Chicago White Sox, and he has a 9-5 record, 3.31 ERA and 1.27 WHIP.

Houston Astros Preview

The Houston Astros have a 50-54 record this season and are sitting in the 3rd place of the AL West. They have a 24-27 away record and are coming off a 5-2 home win against the Marlins. They will face the Angels and the Rangers next.

The Houston Astros have a .242 batting average this season, .315 OBP and .413 Slugging percentage. Houston’s pitching staff has a 4.71 ERA and 1.39 WHIP. Yordan Alvarez is the team’s best hitter with a .328 batting average, leads the team in RBI with 77, and adds a team-high 34 home runs.

Spencer Arrighetti (R) is the projected starting pitcher for the Houston Astros, and he has a 7-5 record, 4.34 ERA and 1.31 WHIP.

Houston Astros @ the Chicago White Sox Betting Trends: July 24, 2026

• Probable Starting Pitcher: Davis Martin      Record this season: 9-5      ERA: 3.31
• Home Record: 5-1
• Last 5 against Astros: 0-1

Why the Chicago White Sox will win

• The Astros have lost each of their last seven road games against American League opponents following a home win.
• The White Sox have won eight of their last nine home games against AL West opponents.
• The Astros have failed to cover the run line in each of their last five road games against American League opponents following a home win.
• The White Sox have covered the run line in seven of their last eight home games against AL West opponents following a win.
• The Astros have trailed after 3 innings in five of their last six road games against American League opponents.
• The Astros have trailed after 5 innings in five of their last six road games against American League opponents.

• Probable Starting Pitcher: Spencer Arrighetti      Record this season: 7-5      ERA: 4.34
• Road Record: 4-4
• Last 5 against White Sox: 0-1

Why the Houston Astros will win

• The White Sox have lost eight of their last nine games as favorites following a road win.
• The Astros have won three of their last four games as underdogs against AL Central opponents.
• The White Sox have failed to cover the run line in each of their last 11 games as favorites following a road win.
• The Astros have covered the run line each of their last five games against teams that held a winning record.
• The Astros have led after 3 innings in each of their last five games at Rate Field against opponents that held a winning record.
• The Astros have won the first inning in three of their last four games against AL Central opponents that held a winning record.
• The Astros have led after 5 innings in each of their last five games at Rate Field against opponents that held a winning record.

Total Runs Facts

• Each of the Astros’ last five road games against American League opponents have gone OVER the total runs line.
• Four of the White Sox’s last five night games against American League opponents have gone OVER the total runs line.
• There has been no run scored during the first inning in each of the White Sox’s last six night games at Rate Field.
• There has been no run scored during the first inning in each of the Astros’ last four road games against AL Central opponents.

Chicago White Sox Player Prop Facts

• Sam Antonacci has hit a home run in three of his last four appearances after not playing the previous day.
• Davis Martin has recorded a win in three of his last four appearances against AL West opponents.
• Davis Martin has recorded five or more strikeouts in five of his last six appearances against AL West opponents.
• Sam Antonacci has recorded at least one hit in each of his last eight appearances after not playing the previous day.
• Colson Montgomery ranks T9th in the league in Home Runs (24) this season.

Houston Astros Player Prop Facts

• Yordan Alvarez has hit at least one home run in each of the Astros’ last four night games against AL opponents that held a winning record.
• Yordan Alvarez has recorded two or more hits in each of the Astros’ last six games against opponents that held a winning record.
• Spencer Arrighetti has recorded six or more strikeouts in five of his last six appearances against AL opponents.
• Yordan Alvarez ranks 1st in the league in Home Runs (34) this season.

Matchup/League Facts

• The White Sox rank T24th in the league for hits this season (809).
• The White Sox rank T24th in the league for hits this season (809).
• The Astros rank 30th in the league for walks allowed this season (453).
• The Astros rank 30th in the league for walks allowed this season (453).

Astros vs White Sox Prediction

Both teams are tied 3-3 in their last 6 meetings and are 2-2 in their last 4 meetings in Chicago.

In this Astros vs White Sox Prediction, the White Sox are coming as -130 home favorites. I like the White Sox in this one at home with Davis Martin on the bump, who has been elite when pitching in Chicago, with a 5-1 record and 1.80 ERA. On the flip side, Spencer Arrighetti has been all over the place lately, alternating one run games with 8-run games, so I certainly don’t trust them, especially on the road. The White Sox are one of the best home teams in baseball and are 7-2 in their last 9 games, while having both a better offense and a better bullpen. Take the White Sox to win this one.