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Athletics vs Cubs Prediction 4/2/25 MLB Picks Today

Chicago Cubs (4-4) vs. Oakland Athletics (2-4)
April 2, 2025 3:35 pm EDT
The Line: Oakland Athletics -110 / Chicago Cubs -110; Over/Under: 8.5
(Get latest betting odds)

The Chicago Cubs and Athletics meet on Wednesday in MLB action at Sutter Health Park. Here’s an Athletics vs Cubs Prediction. This article will include an Athletics vs Cubs Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 4-4 on the year and play the Padres, Rangers, and Dodgers next. The Chicago Cubs are batting .251 on the season, have a .335 OBP, and a .447 slugging percentage. The Chicago Cubs pitching staff has a 5.53 ERA and a 1.60 WHIP. Kyle Tucker leads the Chicago Cubs with 12 hits and 11 RBI, while Dansby Swanson and Seiya Suzuki have combined for 16 hits and 12 RBI.


Jameson Taillon gets the ball for the Chicago Cubs, and he is 0-1 with a 12.46 ERA and 1 strikeout this season. Taillon is 2-0 with a 5.12 ERA and 17 strikeouts in his career against the Athletics.

Athletics Betting Preview

The Athletics are 2-4 on the year and play the Rockies, Padres, and Mets next. The Athletics are batting .228 on the season, have a .284 OBP, and a .401 slugging percentage. The Athletics’ pitching staff has a 4.85 ERA and a 1.52 WHIP. Tyler Soderstrom leads the Athletics with 8 hits and 4 RBI, while Brent Rooker and Jacob Wilson have combined for 13 hits and 7 RBI.

Jeffrey Springs gets the ball for the Athletics, and he is 1-0 with a 0.00 ERA and 9 strikeouts this season. Springs is 0-0 with a 0.00 ERA and 3 strikeouts in his career against the Chicago Cubs.

Why the Athletics will win

  • The Athletics have won eight of their last nine day games against NL Central opponents.
  • The Cubs have lost five of their last six road games following a win.
  • The Athletics have covered the run line in nine of their last 10 day games against NL Central opponents.
  • The Cubs have failed to cover the run line in five of their last six road games following a win.
  • The Athletics have led after 5 innings in eight of their last 10 day games against NL Central opponents.

Why the Chicago Cubs will win

  • The Cubs have won each of their last nine games against AL West opponents following a road win.
  • The Athletics have lost each of their last seven home games against the Cubs following a loss.
  • The Cubs have covered the run line in each of their last 10 day games against AL West opponents following a road win.
  • The Athletics have failed to cover the run line in each of their last seven home games after playing the previous day.
  • The Cubs have won the first inning in each of their last three road games against AL West opponents.
  • The Athletics have trailed after 3 innings in each of their last five home games against National League opponents.
  • The Cubs have led after 5 innings in each of their last four games.

Athletics vs Cubs Prediction

The Cubs have found their offense in this series, scoring 25 runs in two games, and they’ve scored four or more runs in four straight games. The Athletics aren’t enjoying Sacramento, to say the least, and it’s hard to back them with confidence, given how the first two games have gone.

Taillon can’t be any worse than he was in his season opener, and a bounce-back is expected, given how his first couple of seasons with the Cubs have gone. I’m just not running to the window to back the Athletics after they’ve gotten curb-stomped in this series. I like the Cubs to sweep the Athletics.

Randy Chambers's Free Pick: Chicago Cubs -110

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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