Blue Jays vs Guardians Prediction 5/3/25 MLB Picks Today

The Cleveland Guardians and the Toronto Blue Jays meet Saturday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Blue Jays vs Guardians Prediction.

Starting Pitching Matchup

The Cleveland Guardians will send out Gavin Williams for the start here, and he is 2-2 with a 5.14 ERA and 28 strikeouts this season. This will be Williams’ second career start against the Blue Jays. The Toronto Blue Jays will trot out Kevin Gausman for the start here, and Gausman is 2-3 with a 4.50 ERA and 28 strikeouts this season. In his last five starts against the Guardians, Gausman is 2-3 with a 3.16 ERA and 29 strikeouts.

Cleveland Guardians Recap

The Cleveland Guardians come into this game looking to bounce back from a 5-3 loss at the hands of the Blue Jays in Friday’s opener to fall to 18-14 on the year. After this series, the Guardians will head on the road for a series against the Nationals.

Guardians Have Three-Game Win Streak Snapped

Steven Kwan leads the Guardians with 41 hits as part of a .323 batting average and 4 home runs, 6 doubles, and 15 RBIs. Kyle Manzardo has 21 hits with 3 doubles, a triple, 8 home runs, and a team-high 20 RBIs as well this year. Gabriel Arias has a team-high 6 doubles, but also has a team-high 31 strikeouts, and Manzardo has 29 strikeouts so far this season. Arias has also added 4 home runs and 11 RBIs, and Jose Ramirez has chipped in 5 home runs and 15 RBIs.

Why the Cleveland Guardians will win

• The Guardians have won five of their last six games as underdogs against the Blue Jays following a loss.
• The Blue Jays have lost each of their last five day games against American League opponents following a win.
• The Guardians have covered the run line in each of their last six games against the Blue Jays following a loss.
• The Blue Jays have failed to cover the run line in each of their last six day games against the Guardians following a win.

Cleveland Guardians Player Prop Facts

• Carlos Santana has recorded at least one Single in each of his last six appearances with his team as a road underdog against AL East opponents.
• Carlos Santana has hit a home run in each of his last five road appearances against the Blue Jays.
• Carlos Santana has recorded at least one RBI in seven of his last eight appearances against the Blue Jays.
• Carlos Santana has recorded at least one hit in each of his last 10 appearances with his team as a road underdog against AL East opponents.
• Carlos Santana has scored at least one run in seven of his last eight appearances with the Guardians as underdogs against the Blue Jays.
• Steven Kwan has recorded a Double in three of the Guardians’ last four games as underdogs against AL East opponents.

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to build on their win over the Guardians on Friday to get back to .500 at 16-16 on the year. After this series, the Blue Jays will head on the road for a series against the Los Angeles Angels.

Blue Jays Win Three In A Row

George Springer has 27 hits and Bo Bichette has 39 hits, with Springer adding 3 home runs, a triple, 7 doubles, and 13 RBIs while Bichette has 10 doubles and 13 RBIs. Andres Gimenez has added 20 hits with 4 doubles and 3 home runs and 8 RBIs this season, along with 8 stolen bases, while Anthony Santander has a team-high 31 strikeouts so far this season. Vladimir Guerrero Jr. also has 4 homers, 6 doubles, and 17 RBIs, while Springer also has a .314 batting average up to this point in the year.

Why the Toronto Blue Jays will win

• The home team has won each of the last six games between the Guardians and Blue Jays.
• The Guardians have lost seven of their last eight road games against AL East opponents.
• The Blue Jays have covered the run line in each of their last six games as home favorites.
• The Guardians have failed to cover the run line in seven of their last eight games as road underdogs against AL East opponents.

Toronto Blue Jays Player Prop Facts

• George Springer has hit at least one home run in three of the Blue Jays’ last four home games against AL Central opponents.
• George Springer has recorded a Double in each of the Blue Jays’ last three day games against AL opponents that held a winning record.
• George Springer has recorded at least one RBI in each of the Blue Jays’ last four home games against AL Central opponents.
• Kevin Gausman has recorded a win in each of his last seven appearances with the Blue Jays as favorites against AL opponents.
• Daulton Varsho has scored at least one run in eight of his last nine home appearances after playing the previous day.
• Alejandro Kirk has recorded at least one Single in each of his last six home appearances after playing the previous day.
• Kevin Gausman has recorded six or more strikeouts in each of his last 12 Saturday appearances with the Blue Jays as favorites.
• Alejandro Kirk has recorded at least one hit in each of his last 11 appearances in day games against teams that held a winning record.
• George Springer ranks 4th amongst qualified players for On Base Percentage (.423) this season.

Total Runs Facts

• Each of the Blue Jays’ last seven games as favorites have gone UNDER the total runs line.
• Each of the Guardians’ last four games have gone UNDER the total runs line.

Blue Jays vs Guardians Prediction

I’m on the over here. I think that this is going to be a higher-scoring game because Kevin Gausman’s heavily relied on splitter is not a mystery anymore, and I think teams are really starting to hone in and figure it out. On the other side, Gavin Williams has been one of the least reliable arms in the Guardians’ rotation up to this point, and the Blue Jays’ bats have been heating up in recent weeks. I think once the bullpens have their say, we get up and over this number, so give me the over here.