Blue Jays vs White Sox Prediction 6/21/25 MLB Picks Today

In this article we will formulate a Blue Jays vs White Sox prediction for this MLB game on Saturday, June 21st at the Rogers Centre in Toronto, Ontario. Let’s take a look at the prediction for this MLB matchup. 

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 40-35 this season after they lost game one by a score of 7-1 on Friday night. Toronto allowed the first seven runs in the game and they never had a chance to make a comeback. The Blue Jays recorded seven hits in the game and they were led by Bichette, who went 3-4 with one RBI in the loss. Toronto started Turnbull, who allowed five hits and four earned runs over 2.0 innings for the loss, while Fluharty allowed three earned runs in relief. 

Prior to this series, the Blue Jays won two out of three against the Diamondbacks, but lost all three against the Phillies before that. Toronto has lost five of their last seven games and they are currently third in the AL East standings. The Toronto pitching staff has a 4.27 ERA with a 1.25 WHIP and a .240 opponent batting average, while their offense has scored 321 runs with a .255 batting average and a .324 on base percentage this season. Bo Bichette has led Toronto with 10 home runs and 45 RBIs, while George Springer has added 10 home runs and 32 RBIs this year. The projected starting pitcher for Toronto is Jose Berrios, who is 2-3 with a 3.81 ERA and a 1.29 WHIP over 87.1 innings pitched this season. 

Chicago White Sox Betting Preview

The Chicago White Sox are 24-52 this year after they defeated Toronto by a score of 7-1 on Friday. Chicago led 7-0 in the third inning, which was enough for the win, but they didn’t score over the final six innings. The White Sox recorded nine hits in the game and they were led by Rojas, Benintendi, and Robert Jr., who all had two RBIs in the win. Chicago started Taylor, who was an opener, while Alexander allowed four hits and zero earned runs over 4.0 innings for the win. 

Prior to this series, the White Sox lost all three against the Cardinals and all three against the Rangers. Chicago has lost eight of their last nine games and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.20 ERA with a 1.40 WHIP and a .255 opponent batting average, while the offense has scored 267 runs with a .223 batting average and a .295 on base percentage this season. Miguel Vargas has led Chicago with 10 home runs and 32 RBIs, while Luis Robert has added seven home runs and 30 RBIs this year. The projected starting pitcher for Chicago is Aaron Civale, who is 1-3 with a 4.67 ERA and a 1.48 WHIP over 27.0 innings pitched this year. 

Why the Blue Jays will beat the White Sox

• The White Sox have lost 14 of their last 15 road games against American League opponents following a road win.
• The Blue Jays have won 12 of their last 14 games against the White Sox.
• The White Sox have failed to cover the run line in five of their last six road games against AL East opponents following a win.
• The Blue Jays have covered the run line in five of their last six day games against the White Sox following a loss.
• The White Sox have trailed after 5 innings in each of their last five day games against AL East opponents that held a winning record.
• The Blue Jays have led after 3 innings in five of their last six day games against the White Sox.

Total Runs Facts

• Eight of the White Sox’s last nine day games against AL East opponents have gone UNDER the total runs line.
• Seven of the Blue Jays’ last eight games against American League opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 12 of the last 13 games between the White Sox and Blue Jays.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the White Sox’s last eight games at Rogers Centre.

Toronto Blue Jays Player Prop Facts

• Bo Bichette has hit a home run in three of the Blue Jays’ last five home games.
• Ernie Clement has recorded a Double in four of the Blue Jays’ last five home games against AL opponents.
• Alejandro Kirk has recorded at least one RBI in eight of his last nine appearances with the Blue Jays as home favorites against AL opponents.
• Jose Berrios has recorded a win in each of his last four home appearances against AL Central opponents that held a losing record.
• Vladimir Guerrero Jr. has scored at least one run in 11 of the Blue Jays’ last 12 games as favorites against AL opponents.
• Jose Berrios has recorded five or more strikeouts in each of his last 17 appearances in day games against AL teams that held a losing record.
• Daulton Varsho has recorded at least one hit in each of his last 11 home appearances against opponents that held a losing record.

Chicago White Sox Player Prop Facts

• Andrew Benintendi has hit a home run in each of the White Sox’s last two games as underdogs.
• Andrew Benintendi has recorded at least one RBI in four of the White Sox’s last five games against AL East opponents.
• Miguel Vargas has scored at least one run in seven of the White Sox’s last eight games.
• Aaron Civale has recorded four or more strikeouts in eight of his last nine appearances with his team as an underdog.
• Luis Robert has recorded at least one hit in each of the White Sox’s last six road games against AL opponents that held a winning record.

Blue Jays vs White Sox Prediction 

Chicago picked up a much needed win on Friday night to snap their losing streak and they have scored at least six runs in two straight games. The White Sox are 8-31 on the road this year, while the Blue Jays are 24-15 at home. Toronto is trying to keep some momentum, but they have struggled over the last week. The Jays are starting Berrios, who has allowed one earned run or fewer in three of his last four starts. The White Sox are going with Civale, who has allowed two earned runs or fewer in five straight starts. I do like how Civale has limited the damage, but Berrios should have little issue with this Chicago lineup. Take Toronto by at least two runs here.