Boston Red Sox vs Milwaukee Brewers Prediction 4/6/26 MLB Picks Today
Milwaukee Brewers (7-2) vs. Boston Red Sox (2-7)
April 6, 2026 6:45 pm EDT
The Line: Boston Red Sox -105 / Milwaukee Brewers -115; Over/Under: 8
(Get latest betting odds)
The Milwaukee Brewers and the Boston Red Sox meet Monday in MLB action from Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Milwaukee Brewers vs. Boston Red Sox prediction.
Starting Pitching Matchup
The Milwaukee Brewers will send out Brandon Woodruff for the start here and Woodruff is 1-0 with a 3.60 ERA and 6 strikeouts this season. This will be Woodruff’s second career start against the Red Sox. Brayan Bello will start for the Red Sox and is 0-1 with a 9.64 ERA and 2 strikeouts this season. In his career, Bello is 0-0 with a 3.86 ERA and 5 strikeouts against the Brewers.
Milwaukee Brewers Recap
The Milwaukee Brewers come into this game looking to add on to their 8-5 win over Kansas City last time out to sit at 7-2 this season. After this series, the Brewers will head home for a series against the Washington Nationals.
Brewers Win Third Straight Series To Start Year
Brice Turang has 10 hits with 4 doubles, a triple, a home run and 6 RBIs while Christian Yelich has 12 hits with a double, a triple, a home run and a team-high 8 RBIs this season. Jake Bauers has added 7 hits with 2 homers and 5 RBIs and Gary Sanchez also has 3 homers with 5 RBIs this season. William Contreras has chipped in 8 hits with 4 doubles with 7 RBIs as well on the year. Garrett Mitchell also has 7 hits with 3 doubles, a home run and 11 RBIs as well on the year.
Why the Milwaukee Brewers will win
- The Red Sox have lost each of their last eight games after playing the previous day.
- The Brewers have won 11 of their last 13 games against American League opponents that held a losing record.
- The Red Sox have failed to cover the run line in each of their last seven games after playing the previous day.
- The Brewers have covered the run line in eight of their last nine road games against the Red Sox.
Milwaukee Brewers Player Prop Facts
- Brandon Woodruff has recorded a win in each of his last seven appearances in night games against teams that held a losing record.
- Brandon Woodruff has recorded eight or more strikeouts in each of his last three appearances against opponents that held a losing record.
- Christian Yelich has recorded at least one hit in each of his last 11 appearances against the Red Sox.
- Gary Sanchez has hit a home run in each of his last two appearances after playing the previous day.
- Christian Yelich ranks T8th in the league in Hits (12) this season.
Boston Red Sox Recap
The Boston Red Sox come into this game looking to shake off an 8-6 loss at the hands of the San Diego Padres last time out to sit at 2-7 this season. After this series, the Red Sox will head on the road for a series against the St. Louis Cardinals.
Red Sox Lose 7 Of Last 8
Wilyer Abreu leads the Red Sox with 15 hits including 4 doubles, a triple, 3 home runs and 7 RBIs while Trevor Story has a homer and 2 RBIs and Marcelo Mayer’s added 5 hits with 3 doubles as well. Roman Anthony has 8 hits with a triple, a home run and 2 RBIs so far this season while Jarren Duran has 6 hits with a pair of doubles as well this season.
Why the Boston Red Sox will win
- The Brewers have lost eight of their last nine games as road favorites against American League opponents.
- The Red Sox have won five of their last six games as home underdogs after playing the previous day.
- The Brewers have failed to cover the run line in each of their last nine games as road favorites after playing the previous day.
- The underdogs have covered the run line in nine of the last 10 games between the Brewers and Red Sox.
Boston Red Sox Player Prop Facts
- Wilyer Abreu has hit at least one home run in three of his last four appearances against NL Central opponents.
- Trevor Story has recorded at least one hit in each of his last 13 home appearances against NL Central opponents that held a winning record.
- Wilyer Abreu ranks 2nd amongst qualified players for Slugging Percentage (.857) this season.
Total Runs Facts
- Seven of the Red Sox’s last eight games as home underdogs have gone UNDER the total runs line.
- Four of the Brewers’ last five games have gone OVER the total runs line.
Milwaukee Brewers vs. Boston Red Sox Prediction
I’m on the Brewers here. I just think that Milwaukee’s the better team by a fair margin in this matchup, and Woodruff is still viewed by many as the staff ace of this rotation. On the flipside, Bello can be hit or miss on the mound and the Red Sox have been doing a lot of missing at the plate this season. I’ll roll with Milwaukee here.