Brewers vs Astros Prediction 5/6/25 MLB Picks Today

The Houston Astros and Milwaukee Brewers meet Tuesday in MLB action at American Family Field. Here’s a Brewers vs Astros Prediction. This article will include a Brewers vs Astros Pick.

Houston Astros Betting Preview

The Houston Astros are 17-17 on the year and play the Reds, Royals, and Rangers next. The Houston Astros are batting .243 on the season, have a .312 OBP, and a .367 slugging percentage. The Houston Astros pitching staff has a 3.41 ERA and a 1.14 WHIP. Jeremy Pena leads the Houston Astros with 36 hits and 12 RBI, while Jose Altuve and Isaac Paredes have combined for 67 hits and 28 RBI.

Hayden Wesneski gets the ball for the Houston Astros, and he is 1-2 with a 3.86 ERA and 26 strikeouts this season. Wesneski is 1-0 with a 1.86 ERA and 14 strikeouts in his career against the Milwaukee Brewers.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 18-18 on the year and play the Rays, Guardians, and Twins next. The Milwaukee Brewers are batting .240 on the season, have a .317 OBP, and a .359 slugging percentage. The Milwaukee Brewers pitching staff has a 4.23 ERA and a 1.33 WHIP. Brice Turang leads the Milwaukee Brewers with 41 hits and 16 RBI while Jackson Chourio and Sal Frelick have combined for 74 hits and 33 RBI.

Chad Patrick gets the ball for the Milwaukee Brewers, and he is 1-3 with a 2.87 ERA and 26 strikeouts this season. This will be Patrick’s first career game against the Houston Astros.

Why the Milwaukee Brewers will win

• The Astros have lost nine of their last 10 road games against NL Central opponents.
• The Brewers have won 14 of their last 16 night games against American League opponents.
• The Astros have failed to cover the run line in 10 of their last 11 games against NL Central opponents.
• The Brewers have covered the run line in seven of their last eight night games against AL West opponents.
• The Brewers have led after 3 innings in each of their last eight games against AL West opponents.
• The Astros have trailed after 5 innings in each of their last six night games.

Why the Houston Astros will win

• The Astros have won five of their last six games as road underdogs following a loss.
• The Brewers have lost five of their last seven games as favorites against the Astros following a win.
• The Astros have covered the run line in 14 of their last 16 games as road underdogs following a loss.
• The Brewers have failed to cover the run line in four of their last five night games against the Astros following a win.
• The Astros have led after 3 innings in three of their last four games against the Brewers.

Milwaukee Brewers Player Prop Facts

• Rhys Hoskins has hit a home run in three of the Brewers’ last six games as home favorites.
• William Contreras has recorded an RBI in five of the Brewers’ last six games as favorites.
• William Contreras has scored at least one run in each of the Brewers’ last six Tuesday night games as favorites.
• Brice Turang has recorded at least one Single in nine of his last 10 home appearances against AL opponents.
• Sal Frelick has recorded at least one hit in each of his last nine appearances with the Brewers as home favorites.

Houston Astros Player Prop Facts

• Jake Meyers has recorded at least one RBI in four of his five previous appearances against the Brewers after playing the previous day.
• Jose Altuve has scored at least one run in four of the Astros’ last five games as road underdogs.
• Jeremy Pena has recorded at least one Single in each of the Astros’ last nine games.
• Isaac Paredes has recorded at least one hit in each of the Astros’ last nine night games.
• Yordan Alvarez has hit at least one home run in three of his eight previous appearances against the Brewers.

Brewers vs Astros Prediction

The Astros are having a rough week and while Wesneski has been respectable this season, it’s hard to get behind them unless the price is worth it. In a near pick em spot, I’m going to side with the home team that’s playing the better baseball. That’s the Brewers. Also, Patrick has been great in his rookie season, allowing 29 hits and 10 runs in 31.1 innings. In 16 innings at home, Patrick has a 1.69 ERA and .211 allowed batting average. Pick em’ line, the Brewers, is one of the better bets on Tuesdays MLB card.