Brewers vs Cardinals Prediction 5/25/26 MLB Picks Today

In this article we will formulate a Brewers vs Cardinals prediction for this MLB game on Monday, May 25th at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 30-20 this year after they lost two out of three against the Dodgers by scores of 5-1, 3-11, and 1-5. In game three, Milwaukee led 1-0 in the second inning, but they were outscored 5-0 the rest of the way for the loss. The Brewers recorded seven hits in the game and they were led by Frelick, who went 0-3 with one RBI. Sproat allowed four hits and three earned runs over 4.0 innings for the loss, while Drohan allowed two earned runs in relief. Prior to that series, Milwaukee swept the Cubs in three games and won two out of three against the Twins. 

This season, Milwaukee has a 3.31 ERA with a 1.21 WHIP and a .220 opponent batting average, while they have scored 246 runs with a .246 batting average and a .333 on base percentage. Brice Turang has led the Brewers with seven home runs and 30 RBIs, while Jake Bauers has added seven home runs and 29 RBIs. The projected starting pitcher for Milwaukee is Jacob Misiorowski, who is 4-2 with a 1.89 ERA and a 0.88 WHIP over 57.0 innings pitched this year. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 29-22 this season after they split two games with the Reds by scores of 8-1 and 6-7. In game two, St. Louis scored two runs to tie the game in the ninth, but they failed to score in the 10th or 11th for the loss. The Cardinals recorded nine hits in the game and they were led by Walker, who went 3-4 with one home run and four RBIs. Leahy allowed seven hits and five earned runs over 5.0 innings, while O’Brien picked up the loss in extra innings. Prior to that series, St. Louis lost two out of three against the Pirates, but did win two out of three against the Royals before that. 

This season, St. Louis has a 4.20 ERA with a 1.37 WHIP and a .254 opponent batting average, while they have scored 233 runs with a .242 batting average and a .323 on base percentage. Jordan Walker has led the Cardinals with 15 home runs and 42 RBIs, while Alec Burleson has added seven home runs and 35 RBIs. The projected starting pitcher for St. Louis is Matthew Liberatore, who is 2-2 with a 4.70 ERA and a 1.55 WHIP over 51.2 innings pitched this season. 

Why the Milwaukee Brewers will win

• The Brewers have won each of their last 12 day games against NL Central opponents following a home loss.
• The Cardinals have lost five of their last six day games against National League opponents.
• The Brewers have covered the run line each of their last six day games against NL Central opponents that held a winning record.
• The Cardinals have failed to cover the run line in four of their last five day games against NL Central opponents following a loss.
• The Brewers have won the first inning in each of their last three games as favorites against National League opponents.
• The Brewers have led after 3 innings in each of their last seven games against opponents that held a winning record.
• The Brewers have led after 5 innings in each of their last six games as home favorites.

Why the St. Louis Cardinals will win

• The Cardinals have won eight of their last nine games as road underdogs following a loss.
• The Brewers have lost three of their last four home games after playing the previous day.
• The Cardinals have covered the run line in each of their last nine road games following a loss.
• The Brewers have failed to cover the run line in 17 of their last 21 home games against National League opponents after playing the previous day.
• The Cardinals have led after 3 innings in each of their last five road games against NL Central opponents.
• The Cardinals have led after 5 innings in each of their last four games as road underdogs against NL Central opponents.

Total Runs Facts

• Seven of the Cardinals’ last eight games as road underdogs have gone UNDER the total runs line.
• Four of the Brewers’ last five games have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Cardinals’ last eight games against National League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of Jacob Misiorowski’s last five home appearances as a starter.

Milwaukee Brewers Player Prop Facts

• Andrew Vaughn has hit a home run in each of his last two home appearances against NL Central opponents.
• William Contreras has recorded at least one hit in each of his last eight appearances.
• Jacob Misiorowski ranks 2nd in the league for total Strikeouts (88) this season.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has hit a home run in five of his last 20 road appearances after not playing the previous day.
• Alec Burleson has recorded at least one hit in each of his 11 previous appearances against the Brewers after not playing the previous day.
• Jordan Walker ranks 4th amongst qualified players for Slugging Percentage (.594) this season.

Matchup/League Facts

• The Brewers rank 30th in the league for home runs this season (34).
• The Brewers rank 1st in the league for home runs allowed this season (37).
• The Cardinals rank 29th in the league for strikeouts this season (380).
• The Cardinals rank T28th in the league for triples this season (3).

Brewers vs Cardinals Prediction 

St. Louis comes into this matchup after losing three of their last four games and they have allowed at least six runs in four of their last five. The Cardinals are 16-9 on the road this year, while the Brewers are 16-11 at home. Milwaukee has won three of their last five games and they have scored five runs in all three of those wins. The Brewers are starting Misiorowski, who has allowed zero earned runs in four straight outings, while Liberatore has allowed eight earned runs in his last 9.2 innings. Take the Brewers -1.5 here.