Brewers vs Cardinals Prediction 9/26/26 MLB Picks Today

The St. Louis Cardinals and Milwaukee Brewers meet Saturday in MLB action at American Family Field. Here’s a Brewers vs. Cardinals Prediction. This article will include a Brewers vs. Cardinals Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 77-83 on the year. The St. Louis Cardinals are batting .241 on the season, with a .314 OBP and a .380 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.26 ERA and a 1.35 WHIP. Alec Burleson leads the St. Louis Cardinals with 168 hits and 115 RBI, while Jordan Walker and Ivan Herrera have combined for 309 hits and 170 RBI.

Quinn Mathews gets the ball for the St. Louis Cardinals, and he is 2-3 with a 3.65 ERA and 39 strikeouts this season. This will be Mathews’ first career game against the Milwaukee Brewers.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 101-59 on the year. The Milwaukee Brewers are batting .259 on the season, have a .340 OBP, and have a .402 slugging percentage. The Milwaukee Brewers’ pitching staff has a 3.52 ERA and a 1.18 WHIP. Brice Turang leads the Milwaukee Brewers with 154 hits and 97 RBI, while William Contreras and Jackson Chourio have combined for 299 hits and 166 RBI.

Dustin May gets the ball for the Milwaukee Brewers, and he is 7-9 with a 4.67 ERA and 139 strikeouts this season. May is 1-0 with a 2.53 ERA and 11 strikeouts in his career against the St. Louis Cardinals.

Why the Milwaukee Brewers will win

• The Brewers have won each of their last nine night games after playing the previous day.
• The Cardinals have lost seven of their last eight games at American Family Field.
• The Cardinals have failed to cover the run line in seven of their last eight night games against NL opponents.
• The Brewers have covered the run line in each of their last five games after playing the previous day.
• The Brewers have led after 5 innings in each of their last six home games against NL Central opponents that held a losing record.
• The Brewers have won the first inning in seven of their last eight home games against opponents that held a losing record.
• The Brewers have led after 3 innings in each of their last six night games against NL Central opponents.

Why the St. Louis Cardinals will win

• The Cardinals have won four of their last five road games against NL Central opponents following a loss.
• The Brewers have lost four of their last five Saturday games as favorites against NL Central opponents.
• The Brewers have failed to cover the run line in eight of their last nine games as favorites against the Cardinals following a home win.
• The Cardinals have covered the run line in 11 of their last 13 games as underdogs after playing the previous day.
• The Cardinals have led after 5 innings in each of their last five Saturday games against the Brewers.

Total Runs Facts

• Five of the Brewers’ last six night games against NL Central opponents have gone OVER the total runs line.
• Four of the Cardinals’ last five games have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in each of the Brewers’ last 11 night games at American Family Field.
• There has been at least one run scored in the first inning in each of Quinn Mathews’ last four road appearances as a starter.

Milwaukee Brewers Player Prop Facts

• William Contreras has hit a home run in three of his last four home appearances.
• Joey Ortiz has recorded at least one hit in each of his last 11 appearances against NL opponents.
• Dustin May has recorded four or more strikeouts in each of his last 11 Saturday appearances.

St. Louis Cardinals Player Prop Facts

• Jordan Walker has hit a home run in three of the Cardinals’ last four games as underdogs against the Brewers.
• JJ Wetherholt has recorded two or more hits in four of his last five road appearances after playing the previous day.

Matchup/League Facts

• The Brewers rank 1st in the league for hits this season (1404).
• The Brewers rank 1st in the league for batting average this season (.258).
• The Cardinals rank 3rd in the league for home runs allowed this season (156).
• The Cardinals rank T27th in the league for triples this season (14).

Brewers vs Cardinals Prediction

Mathews has been a bright spot for the Cardinals this season, but he also sees a 2.33 ERA at home balloon to a 4.68 ERA on the road. The Brewers have nothing to play for after clinching the top overall seed, but they’re also still a team that shows up nightly and wins games. May has been hit or miss this season, but he also played 21 games for the Cardinals this season and knows the strengths and weaknesses of this lineup. He should have success against his former team. Give me the Brewers and the RL for max betting value.