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Brewers vs Orioles Prediction 9/20/26 MLB Picks Today

Milwaukee Brewers (97-58) vs. Baltimore Orioles (75-80)
September 20, 2026 7:20 pm EDT
The Line: Baltimore Orioles 168 / Milwaukee Brewers -205; Over/Under: 7.5
(Get latest betting odds)

In this article, we will formulate a Brewers vs Orioles Prediction for this MLB matchup on Sunday, September 20th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Baltimore Orioles Preview

The Baltimore Orioles have a 75-80 record this season and are sitting in the 5th place of the AL East. They have a 36-41 home record and are coming off a 0-1 home loss against the Brewers. They will face the Blue Jays and the Yankees next.

The Baltimore Orioles have a .234 batting average this season, .315 OBP and .395 Slugging percentage. Baltimore’s pitching staff has a 4.12 ERA and 1.34 WHIP. Pete Alonso is the team’s best hitter with a .266 batting average, leading the team in RBI with 105 and adding a team-high 38 home runs.

Brandon Young (R) is the projected starting pitcher for the Orioles, and he has a 9-4 record, 3.65 ERA and 1.37 WHIP.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 97-58 record this season and are sitting in the 1st place of the NL Central. They have a 45-32 away record and are coming off a 1-0 road win against the Orioles. They will face the Phillies and the Cardinals next.

The Milwaukee Brewers have a .258 batting average this season, .341 OBP and .403 Slugging percentage. Milwaukee’s pitching staff has a 3.56 ERA and 1.19 WHIP. Jackson Chourio is the team’s best hitter with a .285 batting average. Brice Turang leads the team in RBI with 93, while Jake Bauers adds a team-high 26 home runs.

Jacob Misiorowski (R) is the projected starting pitcher for the Brewers, and he has a 15-5 record, 1.89 ERA and 0.81 WHIP.

Milwaukee Brewers @ Baltimore Orioles Betting Trends: September 20, 2026

 

  • Probable Starting Pitcher: Brandon Young      Record this season: 9-4      ERA: 3.65
  • Home Record: 2-3
  • Last 5 against Brewers: –

Why the Baltimore Orioles will win

  • The underdogs have won four of the Orioles’ last five games.
  • The Brewers have lost three of their last four games as road favorites following a win.
  • The Brewers have failed to cover the run line in eight of their last nine games as road favorites against AL opponents following a win.
  • The underdogs have covered the run line in each of the Orioles’ last five games.
  • The Brewers have trailed after 5 innings in seven of their last eight Sunday games as road favorites.

 

  • Probable Starting Pitcher: Jacob Misiorowski      Record this season: 15-5      ERA: 1.89
  • Road Record: 8-4
  • Last 5 against Orioles: –

Why the Milwaukee Brewers will win

  • The Brewers have won each of their last seven games against AL East opponents.
  • The Orioles have lost eight of their last nine night games against NL Central opponents that held a winning record.
  • The Orioles have failed to cover the run line in each of their last eight home games against NL opponents following a home loss.
  • The Brewers have covered the run line in nine of their last 10 games against AL East opponents following a road win.
  • The Brewers have won the first inning in eight of their last 10 games as favorites against AL opponents.
  • The Orioles have trailed after 5 innings in five of their last six home games against NL opponents.
  • The Brewers have led after 3 innings in five of their last six night games.

Total Runs Facts

  • Each of the Orioles’ last four night games against NL Central opponents have gone OVER the total runs line.
  • Each of the Brewers’ last four night games after playing the previous day have gone OVER the total runs line.
  • There has been no run scored during the first inning in each of the Orioles’ last seven games as home underdogs against NL opponents.
  • There has been no run scored during the first inning in each of the Brewers’ last six games.

Baltimore Orioles Player Prop Facts

  • Pete Alonso has hit a home run in four of the Orioles’ last five games as underdogs against NL opponents.
  • Brandon Young has recorded five or more strikeouts in each of his last six appearances against NL opponents.
  • Dylan Beavers has recorded at least one hit in each of the Orioles’ last six night games against NL opponents that held a winning record.
  • Brandon Young has recorded a win in three of his last four appearances with the Orioles as underdogs against NL opponents.
  • Pete Alonso ranks T7th in the league in Home Runs (38) this season.

Milwaukee Brewers Player Prop Facts

  • Jackson Chourio has hit a home run in each of the Brewers’ last two night games against AL opponents that held a losing record.
  • Jacob Misiorowski has recorded nine or more strikeouts in three of his last four appearances against AL opponents.
  • William Contreras has recorded at least one hit in each of his last 11 appearances against AL East opponents.
  • Jacob Misiorowski has recorded a win in four of his last five road appearances against opponents that held a losing record.
  • Jacob Misiorowski ranks 1st in the league for total Strikeouts (243) this season.

Matchup/League Facts

  • The Orioles rank 28th in the league for strikeouts against this season (1456).
  • The Orioles rank 4th in the league for walks this season (566).
  • The Brewers rank 1st in the league for hits this season (1363).
  • The Brewers rank 1st in the league for on-base percentage this season (.341).

Brewers vs Orioles Prediction

The Mariners are 8-2 in their last 10 meetings against the Rockies and have won two of their last three visits in Colorado.

In this Brewers vs Orioles Prediction, the Brewers are coming as -200 road favorites. The Orioles are fighting for a wild card spot while the Brewers have nothing to play for. The Orioles have kept both games close and I like them at +1.5 runs in this one. Brandon Young has a 3.65 ERA this season and the Orioles’ bullpen has been excellent lately, with a 2.23 ERA in their last 10 games and the Orioles have been better against right-handed pitching than the Brewers in their last 5 games. Take the Orioles by +1.5 in this one.

Nikos Lagouretos's Free Pick: Baltimore Orioles +1.5

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