Brewers vs Orioles Prediction 9/18/26 MLB Picks Today

In this article, we will formulate a Brewers vs Orioles Prediction for this MLB matchup on Friday, September 18^th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Baltimore Orioles Preview

The Baltimore Orioles have a 75-78 record this season and are sitting in the 5th place of the AL East. They have a 36-39 home record and are coming off a 7-1 road win against the Mets. They will face the Blue Jays and the Yankees next.

The Baltimore Orioles have a .234 batting average this season, .315 OBP and .396 Slugging percentage. Baltimore’s pitching staff has a 4.14 ERA and 1.35 WHIP. Pete Alonso is the team’s best hitter with a .267 batting average, leading the team in RBI with 102 and adding a team-high 37 home runs.

Cade Povich (L) is the projected starting pitcher for the Orioles, and he has a 2-1 record, 4.05 ERA and 1.44 WHIP.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 95-58 record this season and are sitting in the 1st place of the NL Central. They have a 43-32 away record and are coming off a 7-4 road loss against the Pirates. They will face the Phillies and the Cardinals next.

The Milwaukee Brewers have a .259 batting average this season, .342 OBP and .405 Slugging percentage. Milwaukee’s pitching staff has a 3.58 ERA and 1.19 WHIP. Jackson Chourio is the team’s best hitter with a .286 batting average. Brice Turang leads the team in RBI with 93, while Jake Bauers adds a team-high 26 home runs.

Dustin May (R) is the projected starting pitcher for the Brewers, and he has a 7-9 record, 4.49 ERA and 1.29 WHIP.

Milwaukee Brewers @ Baltimore Orioles Betting Trends: September 18, 2026

• Probable Starting Pitcher: Cade Povich      Record this season: 2-1      ERA: 4.05
• Home Record: 2-0
• Last 5 against Brewers: –

Why the Baltimore Orioles will win

• The Orioles have won eight of their last nine games as underdogs against NL opponents following a road win.
• The Brewers have lost four of their last six games as road favorites after playing the previous day.
• The Orioles have covered the run line in each of their last nine games as underdogs against NL opponents following a road win.
• The Brewers have failed to cover the run line each of their last four road games against teams that held a losing record.
• The Brewers have trailed after 3 innings in four of their last five games as road favorites against AL opponents.

• Probable Starting Pitcher: Dustin May      Record this season: 7-9      ERA: 4.49
• Road Record: 2-4
• Last 5 against Orioles: 0-1

Why the Milwaukee Brewers will win

• The Brewers have won eight of their last nine night games against teams that held a losing record.
• The Orioles have lost seven of their last eight night games against NL Central opponents that held a winning record.
• The Orioles have failed to cover the run line in seven of their last eight home games against NL Central opponents.
• The Brewers have covered the run line in seven of their last eight games against AL opponents following a loss.
• The Brewers have led after 3 innings in eight of their last nine night games against opponents that held a losing record.
• The Orioles have trailed after 5 innings in seven of their last eight games as home underdogs against NL opponents.
• The Brewers have won the first inning in eight of their last nine games against AL opponents.

Total Runs Facts

• Seven of the Brewers’ last eight games against AL East opponents have gone UNDER the total runs line.
• Five of the last six games between the Brewers and Orioles have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of the Brewers’ last nine games against AL opponents.
• There has been no run scored during the first inning in each of the Orioles’ last six games as home underdogs against NL opponents.

Baltimore Orioles Player Prop Facts

• Christian Encarnacion-Strand has hit a home run in three of the Orioles’ last four games as underdogs against NL opponents.
• Colton Cowser has recorded at least one hit in each of his last six appearances after not playing the previous day.
• Cade Povich has recorded five or more strikeouts in seven of his last eight home appearances.
• Pete Alonso ranks T8th in the league in Home Runs (37) this season.

Milwaukee Brewers Player Prop Facts

• William Contreras has hit a home run in three of his last four appearances against opponents that held a losing record.
• William Contreras has recorded at least one hit in each of his last nine appearances against AL East opponents.
• Jake Bauers ranks 2nd amongst qualified players for On Base Percentage (.394) this season.

Matchup/League Facts

• The Orioles rank 28th in the league for strikeouts against this season (1439).
• The Orioles rank 28th in the league for hits allowed this season (1328).
• The Brewers rank 1st in the league for hits this season (1350).
• The Brewers rank 1st in the league for on-base percentage this season (.342).

Brewers vs Orioles Prediction

The Brewers are 7-3 in their last 10 meetings against the Orioles and are 3-1 in their last 4 visits in Baltimore.

In this Brewers vs Orioles Prediction, the Brewers are coming as -140 road favorites. I don’t like the pitching in this matchup, as both starters have a 4+ ERA and Dustin May sits on a 5.50 road ERA this season. Both offenses have been red-hot lately, especially Milwaukee’s and they both average 12.5 runs per game combined in their last 10 games and as a result, they are 12-4 to the over in their last 16 games combined. Take the over 8.5 in this one.