Brewers vs Pirates Prediction 4/25/26 MLB Picks Today

In this article we will formulate a Brewers vs Pirates prediction for this MLB game on Saturday, April 25th at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 13-12 this year after they lost game one by a score of 6-0 on Friday night. Milwaukee had a ton of issues at the plate in the game and they barely generated any baserunners. The Brewers recorded one hit and they committed two errors in the game, while they were led by Bauers, who went 1-3. Woodruff allowed five hits and three earned runs over 5.0 innings for the loss, while Drohan allowed one earned run in relief. Prior to this series, Milwaukee lost two out of three against the Tigers, but did win two out of three against the Marlins before that. 

This season, Milwaukee has a 3.98 ERA with a 1.33 WHIP and a .243 opponent batting average, while they have scored 124 runs with a .233 batting average and a .333 on base percentage. Jake Bauers has led the Brewers with five home runs and 15 RBIs, while Garrett Mitchell has added one home run and 18 RBIs. The projected starting pitcher for Milwaukee is Jacob Misiorowski, who is 1-2 with a 3.04 ERA and a 1.09 WHIP over 26.2 innings pitched this year. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 15-11 this season after they won game one by a score of 6-0 last night. Pittsburgh took the lead in the third inning and never looked back in the lopsided win. The Pirates recorded nine hits in the game and they were led by Griffin, who went 3-4 with one home run and three RBIs. Skenes allowed one hit and zero earned runs over 7.0 innings for the win, while Mattson threw a scoreless ninth. Prior to this series, Pittsburgh lost two out of three against the Rangers, but did win two out of three against the Rays before that. 

This season, Pittsburgh has a 3.32 ERA with a 1.25 WHIP and a .220 opponent batting average, while they have scored 129 runs with a .246 batting average and a .330 on base percentage. Oneil Cruz has led the Pirates with eight home runs and 24 RBIs, while Brandon Lowe has added seven home runs and 19 RBIs. The projected starting pitcher for Pittsburgh is Mitch Keller, who is 2-1 with a 2.79 ERA and a 1.10 WHIP over 29.0 innings pitched this season. 

Why the Milwaukee Brewers will win

• The Pirates have lost each of their last nine night games at American Family Field following a road win.
• The Brewers have won 12 of their last 13 night games against the Pirates at American Family Field following a home loss.
• The Brewers have covered the run line in each of their last seven games as favorites against the Pirates.
• The Pirates have failed to cover the run line in each of their last five games following a win.
• The Pirates have trailed after 3 innings in five of their last six games at American Family Field.
• The Brewers have led after 5 innings in each of their last four games as home favorites against NL Central opponents.

Why the Pittsburgh Pirates will win

• The Brewers have lost each of their last seven games against National League opponents following a loss.
• The underdogs have won five of the Brewers’ last seven games at American Family Field.
• The Brewers have failed to cover the run line in 12 of their last 13 home games against National League opponents after playing the previous day.
• The Pirates have covered the run line in each of their last six games against NL Central opponents.
• The Pirates have won the first inning in three of their last four games as underdogs.
• The Pirates have led after 3 innings in six of their last seven games against opponents that held a winning record.
• The Pirates have led after 5 innings in each of their last four road games against opponents that held a winning record.

Total Runs Facts

• Each of the Pirates’ last four night games as underdogs have gone UNDER the total runs line.
• Five of the Brewers’ last six night games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Pirates’ last eight Saturday games against National League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Brewers’ last four games as favorites.

Milwaukee Brewers Player Prop Facts

• Christian Yelich has recorded at least one hit in each of his last 13 appearances with the Brewers as favorites against the Pirates.
• Andrew Vaughn has hit a home run in each of his last two home appearances against NL Central opponents.
• Jacob Misiorowski ranks 5th in the league for total Strikeouts (42) this season.

Pittsburgh Pirates Player Prop Facts

• Marcell Ozuna has hit a home run in three of his last four appearances with his team as a road underdog against the Brewers.
• Mitch Keller has recorded five or more strikeouts in each of his six previous road appearances against the Brewers.
• Bryan Reynolds has recorded at least one hit in each of the Pirates’ last eight games as road underdogs against the Brewers.
• Oneil Cruz ranks T3rd in the league in Steals (10) this season.

Matchup/League Facts

• The Brewers rank 1st in the league for steals this season (35).
• The Brewers rank 28th in the league for hits this season (193).
• The Pirates rank 3rd in the league for ERA this season (3.32).
• The Pirates rank 3rd in the league for home runs allowed this season (19).

Brewers vs Pirates Prediction 

Pittsburgh was able to get the shutout win to start this series on Friday, but they have alternated wins and losses over their last five games. The Pirates are 7-6 on the road this year, while the Brewers are 7-6 at home. Milwaukee has dropped three in a row and they have allowed 5+ runs in four of their last five. This is another great pitching matchup, but I will side with Misiorowski and the Brewers to bounce back with a win.