Brewers vs Reds Prediction 4/4/25 MLB Picks Today

In this article we will formulate a Brewers vs Reds prediction for this MLB game on Friday, April 4th at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 3-4 this season after they defeated Cincinnati by a score of 1-0 in game one of this series. Milwaukee scored the only run in the game on a Frelick single in the fourth inning and their pitching staff did the rest. The Brewers recorded five hits and committed one error in the game, while they were led by Frelick, who went 2-3 with one RBI in the win. Milwaukee started Cortes, who allowed just one hit over 6.0 innings, while Peguero, Hudson, and Payamps combined for three scoreless innings to seal the win. 

Prior to that series, the Brewers won two out of three against the Royals by scores of 3-2, 5-0, and 1-11. The Milwaukee pitching staff has a 6.68 ERA with a 1.40 WHIP and a .243 opponent batting average, while their offense has scored 24 runs with a .218 batting average and a .291 on base percentage this season. Jackson Chourio and Brice Turang have led Milwaukee with one home run and four RBIs each so far this year. The projected starting pitcher for the Brewers is Tyler Alexander, who would most likely be used as an opener. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 2-5 this year after they were shutout by a score of 1-0 to start this series. Cincinnati only scattered two hits in the game and they committed one error, which led to the only run in the game. The Reds were led by Candelario and Trevino, who had both hits for the team. Cincinnati started Lodolo, who allowed just four hits over 6.2 innings, but he did allow an unearned run for the loss. The Reds also lost their last two games against Texas by a score of 1-0, which is the first time that a team has done that in three straight since 1960. 

Prior to this series, the Reds lost two out of three against the Rangers and two out of three against the Giants. The Cincinnati pitching staff has a 2.47 ERA with a 0.85 WHIP and a .174 opponent batting average, while their offense has scored 24 runs with a .197 batting average and a .254 on base percentage this season. Elly De La Cruz has led Cincinnati with two home runs and eight RBIs, while Matt McLain has added three home runs and five RBIs this year. The projected starting pitcher for Cincinnati is Nick Martinez, who is 0-1 with a 6.00 ERA and a 0.83 WHIP over 6.0 innings pitched this year. 

Why the Reds will beat the Brewers

• The Brewers have lost six of their last eight home games against National League opponents following a home win.
• The Brewers have failed to cover the run line in each of their last 10 games against the Reds following a home win.
• The Reds have covered the run line in each of their last nine games against the Brewers following a road loss.
• The Reds have won the first inning in three of their last four night games against National League opponents that held a losing record.
• The Reds have led after 5 innings in each of their last five Friday night games against NL Central opponents that held a losing record.
• The Reds have led after 3 innings in three of their last four night games against NL Central opponents that held a losing record.

Total Runs Facts

• Each of the Reds’ last 10 road games against National League opponents have gone UNDER the total runs line.
• Five of the last six games between the Reds and Brewers at American Family Field have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Reds’ last 10 road games against National League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last four games between the Reds and Brewers.

Milwaukee Brewers Player Prop Facts

• Christian Yelich has hit a home run in five of his last 12 appearances against the Reds.
• Jackson Chourio has recorded at least one hit in each of the Brewers’ last 11 home games.
• Jackson Chourio has recorded a Double in four of the Brewers’ last five home games against opponents that held a losing record.
• Sal Frelick has recorded at least one RBI in three of his last four appearances against the Reds.
• Brice Turang has recorded at least one Single in eight of his last nine appearances after playing the previous day.
• Christian Yelich has scored at least one run in each of his last seven Friday appearances against NL Central teams that held a losing record.

Cincinnati Reds Player Prop Facts

• Tyler Stephenson has scored at least one run in each of his last eight appearances in night games against NL teams that held a losing record.
• Tyler Stephenson has hit a home run in each of his last two appearances in night games against teams that held a losing record.
• Tyler Stephenson has recorded at least one hit in each of his last 14 appearances in night games against teams that held a losing record.
• Spencer Steer has recorded a Double in three of the Reds’ last four night games against NL Central opponents that held a losing record.
• Tyler Stephenson has recorded at least one RBI in seven of his last eight appearances in night games against teams that held a losing record.
• Tyler Stephenson has recorded at least one Single in nine of his last 10 appearances in night games against teams that held a losing record.

Brewers vs Reds Prediction 

Cincinnati comes into this matchup desperately trying to just score one run, as they have been shutout in three straight games. The Reds are 2-5 overall on the season and while their offense has been miserable recently, their pitching staff has been fantastic. Cincinnati will turn to Nick Martinez, who allowed four earned runs over 6.0 innings against the Giants in his first start. Milwaukee is 3-4 on the season, but their offense has also struggled and they don’t have any clear plans for their pitching in this one. I know it seems crazy to side with the Reds during this shutout streak, but I like Martinez and the law of averages says Cincinnati is due. Take the Reds to get a big win here.