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Brewers vs Reds Prediction 9/6/26 MLB Picks Today

Milwaukee Brewers (88-55) vs. Cincinnati Reds (68-74)
September 6, 2026 12:10 pm EDT
The Line: Cincinnati Reds 135 / Milwaukee Brewers -163; Over/Under: 8.5
(Get latest betting odds)

In this article, we will formulate a Brewers vs Reds Prediction for this MLB matchup on Sunday, September 6th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Cincinnati Reds Preview

The Cincinnati Reds have a 68-74 record this season and are sitting in the 5th place of the NL Central. They have a 35-38 home record and are coming off a 5-3 home win against the Brewers. They will face the Dodgers and the Brewers next.

The Cincinnati Reds have a .229 batting average this season, .308 OBP and .398 Slugging percentage. Cincinnati’s pitching staff has a 4.66 ERA and 1.43 WHIP. Elly De La Cruz is the team’s best hitter with a .278 batting average. Sal Stewart leads the team in RBI with 106 and adds a team-high 31 home runs.

Brady Singer (R) is the projected starting pitcher for the Reds, and he has a 5-13 record, 4.83 ERA and 1.45 WHIP.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 88-55 record this season and are sitting in the 1st place of the NL Central. They have a 41-30 away record and are coming off a 3-5 road loss against the Reds. They will face the Cubs and the Reds next.

The Milwaukee Brewers have a .256 batting average this season, .339 OBP and .400 Slugging percentage. Milwaukee’s pitching staff has a 3.51 ERA and 1.18 WHIP. Jackson Chourio is the team’s best hitter with a .283 batting average. Brice Turang leads the team in RBI with 82, while Jake Bauers adds a team-high 23 home runs.

Kyle Harrison (L) is the projected starting pitcher for the Brewers, and he has a 10-4 record, 3.45 ERA and 1.20 WHIP.

Milwaukee Brewers @ Cincinnati Reds Betting Trends: September 6, 2026

 

  • Probable Starting Pitcher: Brady Singer      Record this season: 5-13      ERA: 4.83
  • Home Record: 3-6
  • Last 5 against Brewers: 2-2

Why the Cincinnati Reds will win

  • The Reds have won four of their last five games as underdogs after playing the previous day.
  • The Brewers have lost four of their last six games as favorites.
  • The underdogs have covered the run line in 18 of the Brewers’ last 21 games at Great American Ball Park.
  • The Brewers have failed to cover the run line in six of their last seven day games against NL opponents following a loss.
  • The Brewers have trailed after 3 innings in four of their last five games as favorites.
  • The Brewers have trailed after 5 innings in three of their last four day games against NL Central opponents that held a losing record.

 

  • Probable Starting Pitcher: Kyle Harrison      Record this season: 10-4      ERA: 3.45
  • Road Record: 3-3
  • Last 5 against Reds: 1-1

Why the Milwaukee Brewers will win

  • The Reds have lost each of their last eight home games against the Brewers following a win.
  • The Brewers have won each of their last seven games against the Reds following a road loss.
  • The Brewers have covered the run line in eight of their last nine games against the Reds following a loss.
  • The Reds have failed to cover the run line in five of their last six home games against the Brewers following a home win.
  • The Brewers have led after 3 innings in each of their last six day games against NL opponents.
  • The Brewers have won the first inning in each of their last four day games against opponents that held a losing record.
  • The Brewers have led after 5 innings in each of their last six day games against NL opponents.

Total Runs Facts

  • Each of the Reds’ last four day games against NL opponents have gone OVER the total runs line.
  • Five of the Brewers’ last six day games against NL opponents have gone UNDER the total runs line.
  • There has been at least one run scored in the first inning in each of the last six games between the Brewers and Reds.
  • There has been at least one run scored in the first inning in eight of the Brewers’ last nine games as favorites.

Cincinnati Reds Player Prop Facts

  • Matt Mclain has hit a home run in each of the Reds’ last three home games against NL Central opponents.
  • Brady Singer has recorded five or more strikeouts in five of his last six appearances against NL Central opponents that held a winning record.
  • Sal Stewart has recorded at least one hit in each of the Reds’ last 23 games against NL Central opponents that held a winning record.
  • Sal Stewart ranks T10th in the league in Home Runs (31) this season.

Milwaukee Brewers Player Prop Facts

  • Kyle Harrison has recorded a win in five of his last six appearances in day games.
  • Cooper Pratt has recorded at least one hit in each of his last 13 road appearances.
  • Bo Naylor has hit a home run in three of his last five appearances with his team as a road favorite against NL Central opponents.
  • Jake Bauers ranks 3rd amongst qualified players for On Base Percentage (.392) this season.

Matchup/League Facts

  • The Reds rank 30th in the league for hits this season (1084).
  • The Reds rank 29th in the league for batting average this season (.229).
  • The Brewers rank 1st in the league for hits this season (1246).
  • The Brewers rank 30th in the league for home runs this season (132).

Brewers vs Reds Prediction

The Brewers are 8-2 in their last 10 meetings against the Reds and are 4-1 in their last 5 visits in Cincinnati.

In this Brewers vs Reds Prediction, the Brewers are coming as -155 road favorites. I like the over in this game, as Harrisson has given up 29 runs across his last 7 road starts and has a 4.66 ERA on the road, while Brady Singer has been bad this season with a 4.83 ERA and 1.45 WHIP and has given up at least three runs in each of his last 8 starts. Both offenses have been clicking lately and they combine for 13.5 runs per game against the opposing starter throw hand in their last 5 games. Take the over 8.5 in this one.

Nikos Lagouretos's Free Pick: Over 8.5

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