Cardinals vs Cubs Prediction 7/29/26 MLB Picks Today

In this article we will formulate a Cardinals vs Cubs prediction for this MLB game on Wednesday, July 29th at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 53-54 this year after they lost the first two games in this series by scores of 3-7 and 2-10. In game two, St. Louis allowed the first seven runs in the game and never had a chance in the lopsided loss. The Cardinals recorded seven hits in the game and they were led by Winn, who went 2-4 with one RBI. McGreevy allowed eight hits and seven earned runs over 1.2 innings for the loss, while Svanson allowed one earned run in relief. Prior to this series, St. Louis lost two out of three against the Reds and lost a makeup game with the Diamondbacks. 

This season, St. Louis has a 4.21 ERA with a 1.35 WHIP and a .255 opponent batting average, while they have scored 471 runs with a .239 batting average and a .315 on base percentage. Jordan Walker has led the Cardinals with 22 home runs and 77 RBIs, while Alec Burleson has added 15 home runs and 71 RBIs. The projected starting pitcher for St. Louis is Dustin May, who is 5-7 with a 4.59 ERA and a 1.32 WHIP over 104.0 innings pitched this year. 

Chicago Cubs Betting Preview

The Chicago Cubs are 61-46 this season after they won game two by a score of 10-2 last night. Chicago had their lead cut to 7-1 in the fourth inning, but they answered with the next three runs in the blowout win. The Cubs recorded 17 hits in the game and they were led by Happ, who went 2-4 with two RBIs. Rea allowed four hits and one earned run over 6.0 innings for the win, while Wantz allowed one earned run in relief. Prior to this series, Chicago won two out of three against the Pirates, but lost two out of three against the Tigers before that. 

This season, Chicago has a 4.20 ERA with a 1.27 WHIP and a .245 opponent batting average, while they have scored 558 runs with a .250 batting average and a .341 on base percentage. Dansby Swanson has led the Cubs with 16 home runs and 61 RBIs, while Ian Happ has added 18 home runs and 47 RBIs. The projected starting pitcher for Chicago is Matthew Boyd, who is 6-1 with a 3.81 ERA and a 1.24 WHIP over 59.0 innings pitched this season. 

Why the St. Louis Cardinals will win

• The underdogs have won six of the Cardinals’ last seven games.
• The Cubs have lost each of their last three games as road favorites against the Cardinals following a win.
• The Cardinals have covered the run line in eight of their last nine games as underdogs against National League opponents following a loss.
• The Cubs have failed to cover the run line in five of their last six night games against the Cardinals following a win.
• The Cubs have trailed after 5 innings in five of their last six night games against opponents that held a losing record.
• The Cubs have trailed after 3 innings in four of their last five games at Busch Stadium against opponents that held a losing record.

Why the Chicago Cubs will win

• The Cubs have won 10 of their last 11 games against NL Central opponents that held a losing record.
• The Cardinals have lost seven of their last eight games against NL Central opponents that held a winning record.
• The Cubs have covered the run line in each of their last eight road games following a win.
• The Cardinals have failed to cover the run line each of their last four home games against teams that held a winning record.
• The Cubs have won the first inning in five of their last six games against opponents that held a losing record.
• The Cardinals have trailed after 5 innings in each of their last four home games against opponents that held a winning record.
• The Cardinals have trailed after 3 innings in four of their last five games against NL Central opponents that held a winning record.

Total Runs Facts

• Seven of the Cubs’ last eight games after playing the previous day have gone OVER the total runs line.
• Four of the last five games between the Cubs and Cardinals have gone OVER the total runs line.
• There has been at least one run scored in the first inning in eight of the Cubs’ last nine games as favorites.
• There has been at least one run scored in the first inning in each of the last four games between the Cubs and Cardinals.

St. Louis Cardinals Player Prop Facts

• Dustin May has recorded seven or more strikeouts in each of his last four appearances against NL Central opponents.
• JJ Wetherholt has recorded at least one hit in each of the Cardinals’ last eight games against the Cubs.
• Jimmy Crooks has hit a home run in two of his last three appearances with the Cardinals as underdogs against NL opponents.
• Alec Burleson ranks 9th in the league in Hits (116) this season.

Chicago Cubs Player Prop Facts

• Alex Bregman has hit a home run in each of the Cubs’ last two road games against opponents that held a losing record.
• Matthew Boyd has recorded a win in four of his last five appearances.
• Matthew Boyd has recorded five or more strikeouts in each of his last eight Wednesday appearances against teams that held a losing record.
• Pedro Ramirez has recorded at least one hit in each of his last eight appearances.
• Pete Crow-Armstrong ranks T4th in the league in Steals (26) this season.

Matchup/League Facts

• The Cardinals rank T2nd in the league for home runs allowed this season (106).
• The Cardinals rank T2nd in the league for home runs allowed this season (106).
• The Cubs rank 1st in the league for walks this season (463).
• The Cubs rank 1st in the league for walks this season (463).

Cardinals vs Cubs Prediction 

Chicago rolls into this matchup after winning four of their last five games and they have scored at least seven runs in four straight. The Cubs are 31-24 on the road this year, while the Cardinals are 27-31 at home. St. Louis has lost four of their last five games and they have allowed 22 runs in their last three. The Cardinals are starting May, who has allowed 1, 5, 2, 0, and 5 earned runs in his last five outings, while Boyd has allowed one earned run or fewer in three of his last four starts. Take the Cubs to win again.