
Cardinals vs Mets Prediction 5/4/25 MLB Picks Today
NY Mets (22-11) vs. St. Louis Cardinals (14-19)
May 4, 2025 1:15 pm EDT
The Line: St. Louis Cardinals 110 / NY Mets -130; Over/Under: 8.5
(Get latest betting odds)
In this article, we will formulate a Cardinals vs Mets prediction for this MLB game on Sunday, May 4, at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup.
New York Mets Betting Preview
The New York Mets (22-11, 9-8 Away) failed to win the last two series; they split with the Nationals and lost to the Diamondbacks. However, the Mets did open this series against the Cardinals with a 9-3 victory. Francisco Alvarez led the offense with three RBI, while Clay Holmes got the win after allowing three runs on eight hits with three strikeouts and no walks over 6.0 innings of work.
This season, the Mets average 4.82 runs per game (10th in the MLB) on a .250/.329/.424 slash line. Regarding pitching, the Mets’ staff has a 2.69 ERA (1st) and 1.21 WHIP (10th). Pete Alonso leads the Mets with a .345 batting average, eight home runs, and 30 RBI this season.
The projected starting pitcher for the Mets is Blade Tidwell, who will get his first start in the MLB on his debut in the majors.
St. Louis Cardinals Betting Preview
The St. Louis Cardinals (14-19, 10-6 Home) beat the Brewers and split the series with the Reds before losing the opening game of the current series against the Mets. The Cards had a 3-2 lead until the 5th inning, when the Mets scored five runs and deservedly secured the win. Sonny Gray took the loss after allowing six runs (four earned) on nine hits with six strikeouts and three walks in 4.1 innings.
This year, the Cardinals average 4.55 runs per game (11th in the MLB) on a .256/.329/.395 triple-slash. When it comes to pitching, the Cardinals’ staff has a 4.31 ERA (21st) and 1.26 WHIP (14th). Lars Nootbaar leads the Cardinals with a .254 batting average, five home runs, and 18 RBI this season.
Erick Fedde will take the mound for the Cardinals on Sunday. The 32-year-old right-hander has a 1-3 record in six starts this year with a 4.68 ERA and 1.35 WHIP in 32.2 innings.
Total Runs Facts
- Five of the Cardinals’ last six home games against NL East opponents have gone UNDER the total runs line.
- Four of the Mets’ last five games as favorites against National League opponents have gone OVER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cardinals’ last six games as underdogs against National League opponents.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Mets’ last five games.
Matchup/League Facts
- The Cardinals are one of only four teams in the league to rank top 10 in both strikeouts and on-base percentage this season.
- The Cardinals rank 27th in the league for strikeouts this season (229).
- The Mets rank 2nd in the league for triples this season (8).
- The Mets rank 2nd in the league for runs allowed this season (101).
Cardinals vs Mets Prediction
The Mets won nine of the previous ten H2H encounters and already have a 5-0 lead in this year’s series. The Mets will start rookie Tidwell, who hasn’t pitched yet in the majors. That is a chance for the Cards to score multiple runs off an inexperienced pitcher, but the Mets will also have an opportunity to score multiple runs off Fedde, who doesn’t have good numbers against them. Fedde allowed a .330 BA in 112 at-bats against the Mets. I am going with Over here.