Cubs vs Mets Prediction 9/23/25 MLB Picks Today

The New York Mets and the Chicago Cubs meet Tuesday in MLB action from Citi Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cubs vs Mets Prediction.

Starting Pitching Matchup

The New York Mets will send out David Peterson here and Peterson is 9-6 with a 3.98 ERA and 149 strikeouts this season. In his last five starts against the Cubs, Peterson is 1-2 with a 4.91 ERA and 20 strikeouts. Cade Horton will start this one for the Cubs and is 11-4 with a 2.66 ERA and 95 strikeouts. This will be Horton’s first career start against the Mets.

New York Mets Recap

The New York Mets come into this game looking to rebound from their 3-2 loss at the hands of the Washington Nationals last time out to sit at 80-76 this season. After this series, the Mets will head on the road for a division series against the Miami Marlins.

Mets Drop Back-To-Back Games

Pete Alonso has 164 hits with 38 doubles, 37 home runs, 122 RBIs and a .274 batting average while Juan Soto has 148 hits with 20 doubles, 35 stolen bases, 42 home runs and 104 RBIs on the year. Francisco Lindor has 166 hits with 31 stolen bases along with 34 doubles, 28 home runs and 80 RBIs while Mark Vientos has 17 home runs and 60 RBIs, but also has 109 strikeouts so far this season. Brandon Nimmo has also added 146 hits with 27 doubles and 24 home runs and 88 RBIs this season. Luis Torrens has also chipped in 14 doubles and Luisangel Acuna has 15 stolen bases as well this season.

Why the New York Mets will win

• The Mets have won each of their last eight games against the Cubs following a loss.
• The Cubs have lost three of their last four games as home favorites against National League opponents.
• The Cubs have failed to cover the run line in seven of their last eight home games against NL East opponents.
• The Mets have covered the run line in seven of their last eight games against the Cubs following a loss.

New York Mets Player Prop Facts

• Pete Alonso has hit a home run in each of the Mets’ last four games against opponents that held a winning record.
• Juan Soto has recorded at least one hit in each of the Mets’ last 12 road games against NL Central opponents.

Chicago Cubs Recap

The Chicago Cubs come into this game looking to rebound from a 1-0 loss at the hands of the Cincinnati Reds last time out to sit at 88-68 this season. After this series, the Cubs will take on the St. Louis Cardinals in a division series at home.

Cubs Drop 4 Straight

Ian Happ has 132 hits with 29 doubles, 23 home runs and 74 RBIs. Kyle Tucker has 132 hits including 25 doubles, 4 triples, 22 home runs and 73 RBIs while Seiya Suzuki also has 133 hits with 30 doubles and 27 home runs and 91 RBIs of his own. Pete Crow-Armstrong also has contributed 140 hits, 37 doubles, 4 triples, 29 home runs and 90 RBIs as well this season. Dansby Swanson has added 23 home runs and 76 RBIs, while also having 165 strikeouts and Suzuki has 159 strikeouts so far this season. Crow-Armstrong also has a team-high 35 stolen bases while Nico Hoerner has 28 stolen bases this season. Tucker’s also added 25 stolen bases while Michael Busch has also chipped in 22 doubles, 4 triples, 30 home runs and 82 RBIs this season.

Why the Chicago Cubs will win

• The Mets have lost each of their last 10 road games against National League opponents that held a winning record.
• The Cubs have won each of their last six games against the Mets following a road loss.
• The Cubs have covered the run line in each of their last eight night games against NL East opponents following a road loss.
• The Mets have failed to cover the run line in seven of their last eight road games.

Chicago Cubs Player Prop Facts

• Ian Happ has hit a home run in each of the Cubs’ last two games as home favorites.
• Nico Hoerner has recorded two hits in each of the Cubs’ last four home games.
• Ian Happ has recorded at least one Double in six of the Cubs’ last eight home games against NL East opponents that held a winning record.

Total Runs Facts

• Each of the Mets’ last eight night games as underdogs have gone OVER the total runs line.
• Eight of the Cubs’ last nine night games against NL East opponents have gone UNDER the total runs line.

Cubs vs Mets Prediction

I’m on the Cubs here. I know the Cubs have clinched, and the Mets are playing with fire with their season hanging in the balance, but Peterson’s not a reliable option in his current form. Cade Horton’s been rock solid this season, maybe Chicago’s best starter consistently. The Mets have been disappointing in far better positions than this, and I think the Cubs take down the series opener here. Give me Chicago.